Good Studies Evaluate the Disease While Great Studies Evaluate the Patient: Development and Application of a Desirability of Outcome Ranking Endpoint for Staphylococcus aureus Bloodstream Infection

机译：好的研究评估疾病而优秀的研究评估患者：金黄色葡萄球菌血流感染结果分级终点的理想性的发展和应用

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BackgroundDesirability of outcome ranking (DOOR) is an innovative approach in clinical trials to evaluate the global benefits and risks of an intervention. We developed and validated a DOOR endpoint for Staphylococcus aureus bloodstream infection (BSI) through a survey to infectious diseases clinicians and secondary analysis of trial data.

机译：背景期望结果分级（DOOR）是临床试验中一种创新的方法，用于评估干预措施的整体收益和风险。通过对传染病临床医生进行调查和对试验数据进行二次分析，我们开发并验证了金黄色葡萄球菌血流感染（BSI）的DOOR终点。

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期刊名称 Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
作者
Sarah B Doernberg; Thuy Tien Tram Tran; Steven Y C Tong; Mical Paul; Dafna Yahav; Joshua S Davis; Leonard Leibovici; Helen W Boucher; G Ralph Corey; Sara E Cosgrove; Henry F Chambers; Vance G Fowler; Scott R Evans; Thomas L Holland;
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年(卷),期 -1(68),10
年度 -1
页码 1691–1698
总页数 8
原文格式 PDF
正文语种
中图分类免疫学;微生物学;病毒传染病;
关键词
clinical trial Staphylococcus aureus bloodstream infection;

机译：临床试验;金黄色葡萄球菌;血液感染;

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专利

1. Good Studies Evaluate the Disease While Great Studies Evaluate the Patient: Development and Application of a Desirability of Outcome Ranking Endpoint for Staphylococcus aureus Bloodstream Infection [J] . Doernberg Sarah B., Thuy Tien Tram Tran, Tong Steven Y. C., Clinical infectious diseases . 2019,第10期

机译：良好的研究评估疾病，而良好的研究评估患者：开发和应用葡萄球菌血液感染的结果排名终点的可取性
2. Evaluation of Fixed-Dose Daptomycin in Obese Patients With Bloodstream Infections Caused by Staphylococcus aureus [J] . The annals of pharmacotherapy . 2020,第3期

机译：肥胖患者固定剂量达托霉素的评价血管金黄色葡萄球菌引起的血流感染患者
3. A Retrospective Analysis of Treatment and Clinical Outcomes among Patients with Methicillin-Susceptible Staphylococcus aureus Bloodstream Isolates Possessing Detectable mecA by a Commercial PCR Assay Compared to Patients with Methicillin-Resistant Staphylococcus aureus Bloodstream Isolates [J] . Jones Dylan, Elshaboury Ramy H., Munson Erik, Antimicrobial agents and chemotherapy. . 2018,第1期

机译：与甲氧西林型金黄色葡萄球菌血栓子分离株的甲氧胞血管分离患者甲氧西林易溶性葡萄球菌患者治疗和临床结果的回顾性分析
4. Pilot Study to Assess the Incidence of Staphylococcus aureus Infections in Newly Calved Dairy Heifers Using PCR on DHI Samples [C] . Ann Godkin, Richard Cantin National Mastitis Council Annual Meeting . 2011

机译：试点研究，评估使用PCR在DHI样品上使用PCR在新分布的乳制品小母牛葡萄球菌感染的发病率
5. A retrospective study to evaluate the efficacy of trimethoprim/sulfamethoxazole (TMP/SMX) compared to Daptomycin or Linezolid for the treatment of infections due to methicillin-resistant Staphylococcus aureus (MRSA). [D] . Poona Murari, Aparna Lakshmi. 2012

机译：回顾性研究评估甲氧苄氨嘧啶/磺胺甲恶唑（TMP / SMX）与达托霉素或利奈唑胺相比在治疗耐甲氧西林金黄色葡萄球菌（MRSA）感染中的疗效。
6. Panton-Valentine Leukocidin Is Not the Primary Determinant of Outcome for Staphylococcus aureus Skin Infections: Evaluation from the CANVAS Studies [O] . Amy Tong, Steven Y. C. Tong, Yurong Zhang, 2009

机译：Panton-Valentine Leukocidin不是金黄色葡萄球菌皮肤感染结果的主要决定因素：来自CANVAS研究的评估
7. Good Studies Evaluate the Disease While Great Studies Evaluate the Patient: Development and Application of a Desirability of Outcome Ranking Endpoint for Staphylococcus aureus Bloodstream Infection [O] . Sarah B Doernberg, Thuy Tien Tram Tran, Steven Y C Tong, 2018

机译：良好研究评估疾病，而良好的研究评估患者：开发和应用葡萄球菌血液感染的结果排名终点的可取性

Good Studies Evaluate the Disease While Great Studies Evaluate the Patient: Development and Application of a Desirability of Outcome Ranking Endpoint for Staphylococcus aureus Bloodstream Infection

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