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Comparative study of rabies antibody titers of dogs vaccinated in Finland and imported street dogs vaccinated abroad

机译:芬兰接种的狗与国外接种的进口流浪狗的狂犬病抗体滴度的比较研究

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摘要

Seventy-two canine serum samples were analyzed for post-vaccination serum titers of rabies antibodies. The samples were divided into two groups: Group 1 dogs (n = 36) were imported dogs from the Russian Federation (n = 31) or Romania (n = 5), with a mean serum antibody titer value of 1.54 IU/mL. Group 2 dogs (n = 36) were Finnish dogs vaccinated in Finland, with a mean titer of 4.19 IU/mL. Altogether, 14 (39%) dogs (CI 95% 23–56) were without detectable antibodies (≤ 0.1 IU/mL) in Group 1, whereas in Group 2, all dogs had an antibody titer greater than 0.1 IU/mL. A statistically significant difference was observed between these groups when comparing the proportions of dogs with antibody levels less than or exceeding 0.5 IU/mL. In Group 1, 19 out of the 36 dogs (CI 95% 36–70) had serum titer values < 0.5 IU/mL, while in Group 2, only 2 dogs had serum titer values < 0.5 IU/mL. Despite the small sample size, this raises concern over the imported dogs having insufficient antibody levels required for international travel and implies that these dogs had perhaps not been vaccinated, even though they had documentation of vaccination upon arrival.
机译:分析了72只犬血清样品的狂犬病抗体的疫苗接种后血清滴度。样品分为两组:第1组狗(n = 36)是从俄罗斯联邦(n = 31)或罗马尼亚(n = 5)进口的狗,平均血清抗体滴度值为1.54IU / mL。第2组犬(n = 36)是在芬兰接种的芬兰犬,平均滴度为4.19 IU / mL。在第1组中,总共有14(39%)只狗(CI 95%23–56)没有可检测的抗体(≤0.1IU / mL),而在第2组中,所有狗的抗体滴度均大于0.1IU / mL。比较抗体水平低于或超过0.5IU / mL的狗的比例时,在这些组之间观察到统计学上的显着差异。在第1组中,36只狗中有19只(CI 95%36–70)的血清滴度值≤0.5IU / mL,而在第2组中,只有2只狗的血清滴度值≤0.5IU / mL。尽管样本量很小,但这引起了对进口犬的国际旅行所需抗体水平不足的担忧,这意味着即使这些犬在抵达时有疫苗接种证明,也可能未进行疫苗接种。

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