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美国卫生研究院文献>Acta Veterinaria Scandinavica
>Reduced use of antimicrobials after vaccination of pigs against porcine proliferative enteropathy in a Danish SPF herd
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Reduced use of antimicrobials after vaccination of pigs against porcine proliferative enteropathy in a Danish SPF herd
The present study explored whether the use of group medication with antibiotics in a Danish pig herd was reduced after vaccination of the pigs against proliferative enteropathy (PE) caused by Lawsonia intracellularis. 7900 pigs originating from a single commercial sow herd were vaccinated against L. intracellularis, whereas 7756 pigs were kept as non-vaccinated controls. The pigs were included batch-wise in the study with every second batch being vaccinated. In the vaccinated batches, the consumption of oxytetracykline to treat PE was reduced by 79%, with a significantly lower number of pigs being treated (P < 0.0001). Vaccination also resulted in a highly significant improvement of average daily weight gain (+ 46 g/day; P = 9.55 × 10-31) and carcase weight (+ 1.25 kg; P = 4.54 × 10-05) as well as a shortened fattening period (-8 days; P = 2.01 × 10-45).
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机译：本研究探讨了在对猪接种细胞内劳森菌引起的增生性肠病（PE）疫苗后，丹麦猪群中抗生素类药物的使用是否减少。对来自单个商业母猪群的7900头猪接种了细胞内劳森氏菌，而将7756头猪作为未接种的对照。将猪分批纳入研究，每第二批接种一次。在接种疫苗的批次中，土霉素治疗PE的消耗量减少了79％，而被治疗的猪数量则明显减少（P <0.0001）。接种疫苗还显着改善了平均每日体重增加（+ 46 g /天； P = 9.55×10 -31 ）和畜体重量（+ 1.25 kg; P = 4.54×10 -05 ），并缩短了育肥期（-8天； P = 2.01×10 -45 ）。
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