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Evaluation of Clinical and Laboratory Variables as Prognostic Indicators in Hospitalised Gastrointestinal Colic Horses

机译:评价临床和实验室变量作为住院胃肠绞痛马的预后指标

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摘要

The present prospective study included 106 horses referred to the Department of Large Animal Sciences, The Norwegian School of Veterinary Science, as non-responders to the initial colic treatment in general practise. In 14 of these cases a required surgical treatment was not performed due to economical or other reasons and were excluded from the study. Clinical and laboratory data were obtained at the arrival in the hospital. The outcome for all analyses was survivalon-survival. A multivariable logistic regression was performed. The analyses were used in medically (46 horses) and surgically treated cases (46 horses) separately. The same analyses were also run for all 92 horses in a simulated "field" situation, where only clinical variables and D-dimer values were included. The fraction of survivors was 78% in the medical and 48% in the surgical cases. In total 63% of the horses survived. In the final multivariable logistic regression model packed cell volume (PCV) was the only important predictor for medically treated cases, and heart rate and presence of hyperaemic or cyanotic mucous membranes were the predictors in the surgically treated cases as well as in the simulated "field" situation. In conclusion, traditional variables as heart rate, mucous membranes and PCV were the important predictors for the outcome in hospitalised colic cases.
机译:目前的前瞻性研究包括转诊给挪威兽医学院大型动物科学系的106匹马,他们对一般的绞痛治疗没有反应。其中有14例由于经济原因或其他原因未进行所需的手术治疗,因此被排除在研究范围之外。在到达医院时获得了临床和实验室数据。所有分析的结果均为生存/非生存。进行了多元逻辑回归。这些分析分别用于医疗(46匹马)和外科手术病例(46匹马)。在模拟的“田间”情况下,还对所有92匹马进行了相同的分析,其中仅包括临床变量和D-二聚体值。在医学上,幸存者的比例为78%,在外科手术中,幸存者的比例为48%。总计63%的马存活。在最终的多变量logistic回归模型中,填充细胞量(PCV)是药物治疗病例的唯一重要预测指标,而心率和充血或紫otic性粘膜的存在是手术病例以及模拟“视野”中的预测指标情况。总之,传统变量如心率,粘膜和PCV是住院绞痛病例结果的重要预测指标。

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