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Long-term Results From a Randomized Controlled Trial to Increase Cancer Screening Among Attendees of Community Health Centers

机译:一项随机对照试验的长期结果以增加社区卫生中心与会人员的癌症筛查

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摘要

>PURPOSE We assessed whether increased cancer screening rates that were observed with Cancer Screening Office Systems (Cancer SOS) could be maintained at 24 months’ follow-up, a period in which clinics were expected to be largely self-sufficient in maintaining the intervention.>METHODS Eight primary care clinics serving disadvantaged populations in Hills-borough County, Fla, agreed to take part in a cluster-randomized experimental trial. Charts of independent samples of established patients aged 50 to 75 years were abstracted, with data collected at baseline (n = 1,196) and at 24 months’ follow-up (n = 1,296). Papanicolaou (Pap) smears, mammography, and fecal occult blood testing were assessed.>RESULTS At 24 months of follow-up, intervention patients had received a greater number of cancer screening tests (mean 1.17 tests vs 0.94 tests, t test = 4.42, P <.0001). In multivariate analysis that controlled for baseline screening rates, secular trends, and other patient and clinic characteristics, the intervention increased the odds of mammograms slightly (odds ratio [OR]) = 1.26; 95% confidence interval [CI], 1.02–1.55; P = .03) but had no effect on fecal occult blood tests (OR = 1.17; 95% CI, 0.92–1.48; P =0.19) or Pap smears (OR = 0.88; 95% CI, 0.0.68–1.15; P = .34).>CONCLUSIONS The Cancer SOS intervention had persistent, although modest, effects on screening at 24 months’ follow-up, an effect that had clearly diminished from results reported at 12 months’ follow-up. Further study is needed to develop successful intervention strategies that are either self-sustaining or that are able to produce long-term changes in screening behavior.
机译:>目的我们评估了癌症筛查办公室系统(Cancer SOS)所观察到的癌症筛查率是否可以维持在随访的24个月内,而在此期间,诊所在很大程度上将是自我诊断的。 >方法:为佛罗里达州希尔斯伯勒县弱势人群服务的八家初级保健诊所同意参加一项整群随机试验。提取了50至75岁已确诊患者的独立样本图,并在基线(n = 1,196)和随访24个月(n = 1,296)时收集了数据。 >结果:在随访的24个月中,干预患者接受了更多的癌症筛查测试(平均1.17测试vs 0.94测试)。 ,t检验= 4.42,P <.0001)。在控制基线筛查率,长期趋势以及其他患者和临床特征的多因素分析中,干预措施稍微增加了乳房X线照片的几率(优势比[OR])= 1.26; 95%置信区间[CI]为1.02-1.55; P = .03),但对粪便潜血测试(OR = 1.17; 95%CI,0.92-1.48; P = 0.19)或巴氏涂片检查(OR = 0.88; 95%CI,0.0.68-1.15; P = .34)。>结论在第24个月的随访中,癌症SOS干预对筛查有持续的影响,尽管作用不大,但这种效果明显与第12个月的随访结果有所减弱。需要开展进一步的研究来开发成功的干预策略,这些策略可以自我维持,也可以在筛查行为方面产生长期变化。

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