Two cases are presented of malignant hyperthermia in black patients. One patient developed signs of malignant hyperthermia during general anesthesia that was successfully treated with dantrolene sodium and cooling. A second patient was retrospectively diagnosed as having an atypical variant of malignant hyperthermia secondary to heat stroke and general anesthesia; this patient subsequently died. These cases illustrate that malignant hyperthermia can occur in blacks despite the very low incidence of this syndrome in nonwhite patients.
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