A study was performed of all patients who underwent either surgery or endoscopic polypectomy for colorectal cancer in Oxford between 1979 and 1983 to ascertain whether any changes had occurred in presentation, diagnosis, treatment or outcome since a previous study from the same centre undertaken between 1966 and 1971. The average number of patients treated annually had increased from 52.8 to 103.4. The growth of the population of the health district was 6.7%. A similar proportion (25%) continued to present as emergencies. There was an improvement in the proportion of cases presenting with Dukes' A and B lesions (54% vs 41%) (P < 0.001), and a decrease in the number of patients with extranodal disease (from 30.4% to 13.3%) (P < 0.001). Only 13.9% of patients underwent colonoscopy before surgery and 14 patients were treated by endoscopic removal alone. In a health district with a slowly growing population, the number of patients presenting with colorectal cancer had increased dramatically over a decade. Colonoscopy has so far made little impact on making an earlier diagnosis. The increase in colorectal cancer has important implications for resource allocation.
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机译：对所有在1979年至1983年间在牛津接受过外科手术或内窥镜息肉切除术的大肠癌患者进行了一项研究，以确定自1966年至1983年间同一中心的先前研究以来，其表现，诊断，治疗或结果是否发生了任何变化。 1971年。每年平均接受治疗的患者人数从52.8增加到103.4。卫生区的人口增长为6.7％。类似的比例（25％）继续作为紧急情况出现。出现Dukes'A和B病变的病例比例有所提高（54％比41％）（P <0.001），结外病患者人数有所减少（从30.4％降至13.3％）（ P <0.001）。仅有13.9％的患者在手术前接受了结肠镜检查，其中14例仅接受了内镜摘除术。在人口缓慢增长的卫生区，十年来患有大肠癌的患者数量急剧增加。迄今为止，结肠镜检查对早期诊断几乎没有影响。大肠癌的增加对资源分配具有重要意义。
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