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Novel treatments for complications after bariatric surgery

机译:减肥手术后并发症的新疗法

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摘要

Bariatric surgery has been considered one of best treatments for obesity. As every surgical procedure—and any medical intervention, it is not exempt of complications, among which leaks, strictures, acute hemorrhages and fistulae highlight. Leaks are more common in the gastro-jejunal anastomosis (GJA) in the case of Roux-en-y Gastric Bypass (RYGB), while in Sleeve Gastrectomy (LSG) they locate in the stapler line. Stenosis can be seen in the gastro-jejunostomy in the RYGB and in the gastric tube in case of the LSG. For each of these complications, many innovative solutions have been developed, including new surgical devices. In spite of promising good results, evidence regarding utility and safeness of these technologies is still scarce. Self-expandable endoscopic stents have been used to treat leaks, with an overall success rate of 80–90 % and a migration rate of 15–35 %. The bear trap-like over-the-scope (Ovesco) clips have been used to treat GI hemorrhages, leaks and even fistulae, with a 70–80 % success rate, although more endoscopic sessions may be needed. Overstitch, an endosurgical suture devices, have been used to treat leaks, fistulae and perforations. Overall, technical success achievement approaches to 90 %, while clinical success ranges from 80 to 90 %, except for leaks closure, where a lower success rate has been observed. Despite of all of these advances, early diagnosis and treatment remains the main strategy to achieve success. In summary, novel therapies for complication management can be very useful, though further studies with larger series are still needed in order to confirm their efficacy and safeness.
机译:减肥手术已被认为是肥胖的最佳治疗方法之一。作为每项外科手术以及任何医疗干预措施,都不能免除并发症,其中包括渗漏,狭窄,急性出血和瘘管。在Roux-en-y胃绕道手术(RYGB)中,胃空肠吻合术(GJA)中的泄漏更为普遍,而在袖状胃切除术(LSG)中,泄漏位于吻合器线中。在LSG的胃空肠吻合术和胃管中可见狭窄。对于这些并发症中的每一种,已经开发了许多创新的解决方案,包括新的外科手术设备。尽管取得了令人鼓舞的良好结果,但仍缺乏有关这些技术的实用性和安全性的证据。自膨胀内窥镜支架已用于治疗渗漏,总成功率为80-90%,迁移率为15-35%。像熊陷阱一样的窥视镜(Ovesco)夹子已被用于治疗胃肠道出血,渗漏甚至瘘管,成功率达70–80%,尽管可能需要进行更多的内窥镜检查。过度缝合是一种外科手术缝合设备,已用于治疗渗漏,瘘管和穿孔。总体而言,技术成功率接近90%,而临床成功率从80%到90%不等,但漏孔闭合率却较低。尽管取得了所有这些进步,早期诊断和治疗仍然是取得成功的主要策略。总之,用于并发症管理的新疗法可能非常有用,尽管为了确认其疗效和安全性仍需要进行更多系列的进一步研究。

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