Serum proteomic profile analysis for endometrial carcinoma detection with MALDI-TOF MS

摘要

IntroductionEndometrial carcinoma is the one of the leading causes of terminal cancer death in women, and the best way to solve it is through an early diagnosis. Serum proteomic profiling is a promising approach to classify disease versus normal and matrix-assisted laser desorption/ionization time of flight mass spectrometry (MALDI-TOF). This analysis is a new potential tool for the diagnosis of human diseases. The objective of our study was to assess the feasibility of mass spectrometry, based on serum proteomic pattern for the discrimination of endometrial carcinoma patients from healthy control patients.