Endothelial Effect of Statin Therapy at a High Dose Versus Low DoseAssociated with Ezetimibe

机译：大剂量对小剂量他汀类药物治疗的内皮效应与依泽替米贝相关

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BackgroundThe effect of statins on the endothelial function in humans remains under discussion. Particularly, it is still unclear if the improvement in endothelial function is due to a reduction in LDL-cholesterol or to an arterial pleiotropic effect.

机译：背景他汀类药物对人内皮功能的影响仍在讨论中。特别是，内皮功能的改善是否是由于LDL-胆固醇的降低或动脉多效性作用尚不清楚。

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期刊名称 Arquivos Brasileiros de Cardiologia
作者
Maristela Magnavita Oliveira Garcia; Carolina Garcez Varela; Patricia Fontes Silva; Paulo Roberto Passos Lima; Paulo Meira Góes; Marilia Galeffi Rodrigues; Maria de Lourdes Lima Souza e Silva; Ana Marice Teixeira Ladeia; Armênio Costa Guimarães; Luis Claudio Lemos Correia;
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作者单位

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年(卷),期 2016(106),4
年度 2016
页码 279–288
总页数 10
原文格式 PDF
正文语种
中图分类心血管疾病;
关键词
Endothelium / physiology Cholesterol Hydroxymethylglutaryl-CoA Reductase Inhibitors / therapeutic use Ezetimibe Anticholesterolemic Agents;

机译：内皮/生理学;胆固醇;羟甲基戊二酰辅酶A还原酶抑制剂/治疗用途;依泽替米贝;抗胆固醇药;

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专利

1. Effect of high-dose statin versus low-dose statin plus ezetimibe on endothelial function: A meta-analysis of randomized trials [J] . YeY., ZhaoX., ZhaiG., Journal of cardiovascular pharmacology and therapeutics . 2012,第4期

机译：大剂量他汀类药物与小剂量他汀类药物联合依泽替米贝对内皮功能的影响：一项随机试验的荟萃分析
2. RESEARCH (Recognized effect of Statin and ezetimibe therapy for achieving LDL-C Goal), a randomized, doctor-oriented, multicenter trial to compare the effects of higher-dose statin versus ezetimibe-plus-statin on the serum LDL-C concentration of Japanese [J] . Takeshi Inazawa, Kentaro Sakamoto, Takahide Kohro, Lipids in Health Disease . 2013,第3期

机译：研究（Statin和ezetimibe疗法对实现LDL-C目标的公认作用），一项以医生为中心的随机，多中心试验，比较高剂量他汀类药物与ezetimibe加他汀类药物对日本人血清LDL-C浓度的影响
3. Pretreatment with high-dose statin, but not low-dose statin, ezetimibe, or the combination of low-dose statin and ezetimibe, limits infarct size in the rat. [J] . Birnbaum Y, Lin Y, Ye Y, Journal of cardiovascular pharmacology and therapeutics . 2008,第1期

机译：用大剂量他汀类药物而不是小剂量他汀类药物，依泽替米贝或低剂量他汀类药物和依泽替米贝的组合进行预处理可限制大鼠的梗塞面积。
4. Comparison of Rest Versus Stress Induced Dyssynchrony During Low Dose Dobutamine Infusion as Predictors of Response to Cardiac Resynchronization Therapy [C] . Suma Valentin, Shall Ajay S., Bangalore Sripal, World Congress on Heart Disease . 2011

机译：低剂量Doy丁胺输注期间休息与应激诱导的脱蛋白的比较作为对心脏重新同步治疗的响应预测因子
5. A comparative study of quality of life in patients with low-and intermediate-risk prostate cancer treated at a single institution: Stereotactic radiotherapy vs. high dose-rate brachytherapy monotherapy vs. high dose-rate brachytherapy boost [D] . Helou, Joelle. 2017

机译：单一机构治疗的中低危前列腺癌患者生活质量的比较研究：立体定向放疗与高剂量率近距离放射疗法单药疗法与高剂量率近距离放射疗法增强
6. Effects of Low Dose versus High Dose Statin Therapy on the Changes of Endothelial Function and Carotid Intima-Media Thickness in Patients with Variant Angina [O] . Kye Hun Kim, Sook Hee Cho, Yi Rang Yim, 2013

机译：低剂量大剂量他汀类药物治疗对变异型心绞痛患者血管内皮功能和颈动脉内膜中层厚度的影响
7. Endothelial Effect of Statin Therapy at a High Dose Versus Low Dose Associated with Ezetimibe [O] . Maristela Magnavita Oliveira Garcia, Carolina Garcez Varela, Patricia Fontes Silva, 2016

机译：高剂量他汀类药物治疗与依泽替米贝相关低剂量的内皮功效
8. Phase 3 Randomized Trial of Low Dose Versus Standard Dose m-BACOD Chemotherapy with rGM-CSF for Treatment of AIDS-Associated Non-Hodgkins Lymphona (ACTG 142) Documentation;Final rept [R] . 1995

机译：第3阶段低剂量随机试验与标准剂量m-BaCOD化疗联合rGm-CsF治疗艾滋病相关非霍奇金淋巴膜（aCTG 142）文献;最终报告

Endothelial Effect of Statin Therapy at a High Dose Versus Low DoseAssociated with Ezetimibe

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