The association of forced expiratory volume in one second and forced expiratory flow at 50 of the vital capacity peak expiratory flow parameters and blood eosinophil counts in exercise-induced bronchospasm in children with mild asthma

摘要

BackgroundExercise-induced bronchoconstriction (EIB), which describes acute airway narrowing that occurs as a result of exercise, is associated with eosinophilic airway inflammation, bronchial hyperresponsiveness. The forced expiratory volume in one second (FEV1) is the most commonly used spirometric test in the diagnosis of EIB in exercise challenge in asthma. Other parameters such as forced expiratory flow at 50% of the vital capacity (FEF50%) and peak expiratory flow (PEF) are used less often in the diagnosis of EIB.