A Grey Box Neural Network Model of Basal Ganglia for Gait Signal of Patients with Huntington Disease

摘要

Introduction:Huntington disease (HD) is a progressive neurodegenerative disease which affects movement control system of the brain. HD symptoms lead to patient’s gait change and influence stride time intervals. In this study, we present a grey box mathematical model to simulate HD disorders. This model contains main physiological findings about BG.