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PPAR-alpha and PPAR-beta expression changes in the hippocampus of rats undergoing global cerebral ischemia/reperfusion due to PPAR-gamma status

机译：PPAR-γ状态引起的全脑缺血/再灌注大鼠海马中PPAR-α和PPAR-β表达的变化

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摘要

BackgroundPeroxisome proliferator-activated receptors (PPARs, including alpha, beta and gamma subtypes) and their agonists have a protective role in treatment of central nervous system (CNS) diseases. The present study was designed to investigate the expression changes of PPAR-alpha, -beta, -gamma and NF-kappa B in the hippocampus of rats with global cerebral ischemia/reperfusion injury (GCIRI) after treatment with agonists or antagonists of PPAR-gamma.

机译：背景过氧化物酶体增殖物激活受体（PPAR，包括α，β和γ亚型）及其激动剂在中枢神经系统（CNS）疾病的治疗中具有保护作用。本研究旨在研究PPAR-γ激动剂或拮抗剂治疗后全脑缺血/再灌注损伤（GCIRI）大鼠海马中PPAR-α，-β，-γ和NF-κB的表达变化。

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期刊名称 Behavioral and Brain Functions : BBF
作者
Ying Luo; Qin He; Ge Kuang; Qingsong Jiang; Junqing Yang;
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作者单位

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年(卷),期 2014(10),-1
年度 2014
页码 21
总页数 11
原文格式 PDF
正文语种
中图分类神经科学;医学行为学;
关键词
Global cerebral ischemia-reperfusion injury Hippocampus Peroxisome proliferator-activated receptors;

机译：全脑缺血再灌注损伤;海马;过氧化物酶体增殖物激活受体;

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专利

1. PPAR-alpha and PPAR-beta expression changes in the hippocampus of rats undergoing global cerebral ischemia/reperfusion due to PPAR-gamma status [J] . Ying Luo, Qin He, Ge Kuang, Behavioral and Brain Functions . 2014,第1期

机译：PPAR-γ状态引起的全脑缺血/再灌注大鼠海马中PPAR-α和PPAR-β表达的变化
2. Modulation of the oxidative stress and inflammatory response by PPAR-gamma agonists in the hippocampus of rats exposed to cerebral ischemia/reperfusion. [J] . Collino M, Aragno M, Mastrocola R, European Journal of Pharmacology: An International Journal . 2006,第1a2期

机译：暴露于脑缺血/再灌注的大鼠海马中PPAR-γ激动剂对氧化应激和炎症反应的调节。
3. Modulation of the oxidative stress and inflammatory response by PPAR-gamma agonists in the hippocampus of rats exposed to cerebral ischemia/reperfusion. [J] . Collino M, Aragno M, Mastrocola R, European Journal of Pharmacology: An International Journal . 2006,第1a2期

机译：暴露于脑缺血/再灌注的大鼠海马中PPAR-γ激动剂对氧化应激和炎症反应的调节。
4. The Effects of ligustrazine on the Expression of Bax protein and Cytochrome C Following Focal Cerebral Ischemia/Reperfusion Injury in Rats [C] . Qiuzhen Zhao, Hua Liu, Huaguang Li International conference on biotechnology, chemical and materials engineering . 2013

机译：川gust嗪对大鼠局灶性脑缺血/再灌注损伤后Bax蛋白和细胞色素C表达的影响
5. Neurologic deficits, memory loss, and histologic consequences of global cerebral ischemia in rats: Role of oxygen free-radical mediated reperfusion injury. [D] . Graham, Jacqueline Ransford. 1990

机译：大鼠全脑缺血的神经系统缺陷，记忆力减退和组织学后果：氧自由基介导的再灌注损伤的作用。
6. Levodopa Improves Cognitive Function and the Deficits of Structural Synaptic Plasticity in Hippocampus Induced by Global Cerebral Ischemia/Reperfusion Injury in Rats [O] . Wenzhu Wang, Xu Liu, Zhengyi Yang, 2020

机译：Levodopa改善了通过全球脑缺血/再灌注损伤在大鼠诱导的海马中结构突触可塑性的认知功能和缺陷
7. PPAR-alpha and PPAR-beta expression changes in the hippocampus of rats undergoing global cerebral ischemia/reperfusion due to PPAR-gamma status [O] . Ying Luo, Qin He, Ge Kuang, 2014

机译：PPAR-γ状态引起的全脑缺血/再灌注大鼠海马中PPAR-α和PPAR-β表达的变化

PPAR-alpha and PPAR-beta expression changes in the hippocampus of rats undergoing global cerebral ischemia/reperfusion due to PPAR-gamma status

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