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Phosphatidylcholine formation by LPCAT1 is regulated by Ca2+ and the redox status of the cell

机译：LPCAT1形成的磷脂酰胆碱受Ca2 +和细胞氧化还原状态的调节

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BackgroundUnsaturated fatty acids are susceptible to oxidation and damaged chains are removed from glycerophospholipids by phospholipase A2. De-acylated lipids are then re-acylated by lysophospholipid acyltransferase enzymes such as LPCAT1 which catalyses the formation of phosphatidylcholine (PC) from lysoPC and long-chain acyl-CoA.

机译：背景技术不饱和脂肪酸易于氧化，并且磷脂酶A2可从甘油磷脂中去除受损的链。然后通过溶血磷脂酰基转移酶（例如LPCAT1）将被去酰基化的脂质再酰基化，该酶催化lysoPC和长链酰基辅酶A形成磷脂酰胆碱（PC）。

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期刊名称 BMC Biochemistry
作者
Eric Soupene; Frans A Kuypers;
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作者单位

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年(卷),期 2012(13),-1
年度 2012
页码 8
总页数 11
原文格式 PDF
正文语种
中图分类分子生物学;
关键词
Lands’ cycle Cysteine oxidation Calcium binding Plasma membrane;

机译：土地循环;半胱氨酸氧化;钙结合;质膜;

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专利

1. Phosphatidylcholine formation by LPCAT1 is regulated by Ca 2+ and the redox status of the cell [J] . Eric Soupene, Frans A Kuypers BMC Biochemistry . 2012,第1期

机译：LPCAT1形成的磷脂酰胆碱受Ca 2+和细胞氧化还原状态的调节
2. Wolfram Syndrome protein, Miner1, regulates sulphydryl redox status, the unfolded protein response, and Ca2+ homeostasis [J] . Ajit S. Divakaruni, Alexander Y. Andreyev, Benjamin G. Neel, EMBO Molecular Medicine . 2013,第6期

机译：Wolfram综合症蛋白Miner1调节巯基氧化还原状态，未折叠的蛋白反应和Ca2 +稳态
3. Ca2+ Ionophore and Phorbol Ester Stimulate Diacylglycerol Formation and Phosphatidylcholine Hydrolysis in Rat Parotid Acinar Cells [J] . Atsushi Yakata, Kazuhiro Suda, Masamichi Noguchi, Japanese Journal of Pharmacology . 1992,第1期

机译：Ca2 +离子载体和Phorbol酯刺激大鼠腮腺腺泡细胞中的二酰基甘油形成和磷脂酰胆碱水解。
4. Phosphatidylcholine biosynthesis inside thenucleus: is it involved in regulating cellproliferation? [C] . Alan N. Hunt, Anthony D. Postle International Symposium on Regulation of Enzyme Activity and Synthesis in Normal and Neoplastic Tissues . 2004

机译：磷脂酰胆碱生物合成中核：它是否参与调节细胞溶解率？
5. Mitochondrial Ca2+/Calmodulin-Dependent Kinase II (CaMKII) Regulates Smooth Muscle Cell Migration and Neointimal Formation via Mitochondrial Ca2+ Uptake and Mobility [D] . Nguyen, Emily Kim. 2019

机译：线粒体CA2 + /钙调霉素依赖性激酶II（CAMKII）通过线粒体CA2 +摄取和移动性调节平滑肌细胞迁移和新内膜形成
6. Wolfram Syndrome protein Miner1 regulates sulphydryl redox status the unfolded protein response and Ca2+ homeostasis [O] . Sandra E Wiley, Alexander Y Andreyev, Ajit S Divakaruni, 2013

机译：Wolfram综合症蛋白Miner1调节巯基氧化还原状态未折叠的蛋白反应和Ca2 +稳态
7. Phosphatidylcholine formation by LPCAT1 is regulated by Ca2+ and the redox status of the cell [O] . Eric Soupene, Frans A Kuypers 2012

机译：LPCAT1形成的磷脂酰胆碱受Ca2 +和细胞氧化还原状态的调节

Phosphatidylcholine formation by LPCAT1 is regulated by Ca2+ and the redox status of the cell

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