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The Gene Set Builder: collation curation and distribution of sets of genes

机译:基因集构建器:基因集的整理整理和分配

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摘要

BackgroundIn bioinformatics and genomics, there are many applications designed to investigate the common properties for a set of genes. Often, these multi-gene analysis tools attempt to reveal sequential, functional, and expressional ties. However, while tremendous effort has been invested in developing tools that can analyze a set of genes, minimal effort has been invested in developing tools that can help researchers compile, store, and annotate gene sets in the first place. As a result, the process of making or accessing a set often involves tedious and time consuming steps such as finding identifiers for each individual gene. These steps are often repeated extensively to shift from one identifier type to another; or to recreate a published set. In this paper, we present a simple online tool which – with the help of the gene catalogs Ensembl and GeneLynx – can help researchers build and annotate sets of genes quickly and easily.
机译:背景技术在生物信息学和基因组学中,有许多应用程序旨在研究一组基因的共同特性。通常,这些多基因分析工具试图揭示顺序,功能和表达上的联系。但是,尽管在开发可以分析一组基因的工具上投入了巨大的精力,但在开发可以帮助研究人员首先编译,存储和注释基因集的工具上投入了最小的精力。结果,制作或访问集合的过程通常涉及繁琐且耗时的步骤,例如为每个单独的基因寻找标识符。通常会广泛重复这些步骤,以从一种标识符类型转换为另一种标识符类型。或重新创建已发布的集。在本文中,我们介绍了一个简单的在线工具,借助Ensembl和GeneLynx基因目录,可以帮助研究人员快速轻松地构建和注释基因集。

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