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Frequency characteristics and risk factors of QT interval prolonging drugs and drug-drug interactions in cancer patients: a multicenter study

机译：延长癌症患者QT间期的频率特征和危险因素以及药物间相互作用的多因素研究

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BackgroundCancer patients may receive a high number of medications with the potential to prolong QT interval and subsequent TdP (torsades de pointes). This study aimed to identify the prevalence of QT prolonging drugs, their TdP risk, QT prolonging drug-drug interactions (QT-DDIs), levels, predictors, and TdP risk of drugs involved in QT-DDIs.

机译：背景癌症患者可能会接受大量药物，可能会延长QT间隔和随后的TdP（扭转性扭转型室速）。这项研究旨在确定QT延长药物的患病率，其TdP风险，QT延长药物-药物相互作用（QT-DDIs），水平，预测因子和涉及QT-DDI的药物的TdP风险。

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期刊名称 BMC Pharmacology Toxicology
作者
Qasim Khan; Mohammad Ismail; Sehrash Khan;
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作者单位

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年(卷),期 2017(18),-1
年度 2017
页码 75
总页数 10
原文格式 PDF
正文语种
中图分类药学;
关键词
QT prolongation QT prolonging drugs QT drug-drug interactions Torsades de pointes Cancer Oncology;

机译：QT延长;QT延长药物;QT药物间相互作用;尖头扭转型手足病;癌症;肿瘤学;

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专利

1. Prevalence of QT interval prolonging drug–drug interactions (QT-DDIs) in psychiatry wards of tertiary care hospitals in Pakistan: a multicenter cross-sectional study [J] . Qasim Khan, Mohammad Ismail, Iqbal Haider, International journal of clinical pharmacy. . 2017,第6期

机译：巴基斯坦高等护理医院精神病病房中QT间隔延长药物 - 药物相互作用（QT-DDIS）的患病率：多中心横截面研究
2. Prevalence of QT interval prolongation in patients admitted to cardiac care units and frequency of subsequent administration of QT interval-prolonging drugs: A prospective, observational study in a large urban academic medical center in the US [J] . TisdaleJ.E., WroblewskiH.A., OverholserB.R., Drug safety: An international journal of medical toxicology and drug experience . 2012,第6期

机译：接受心脏护理病房的患者中QT间隔延长的患病率和随后服用QT间隔延长药物的频率：在美国一家大型城市学术医疗中心进行的一项前瞻性观察性研究
3. Assessment of the risk of QT-interval prolongation associated with potential drug-drug interactions in patients admitted to Intensive Care Units [J] . Flávia Medeiros Fernandes, Aryelle Mayara da Silva Paulino, Bruna Camelo Sedda, Saudi Pharmaceutical Journal . 2019,第2期

机译：评估患者患者收入重症监护单位的患者潜在药物 - 药物相互作用的QT间隔延长的风险
4. A Strategic Approach to Positioning of Cytochrome P450 Studies and Risk Assessment for Drug-Drug Interaction in Drug Discovery [C] . Yamada Yasuhiro International Conference on Cytochrome P450 . 2009

机译：细胞色素P450研究的战略方法，对药物发现中药物互动的研究和风险评估
5. Cardiovascular Adverse Events in Patients Receiving QT Interval Prolonging Medications [D] . Ye, Yizhou. 2017

机译：接受QT间隔延长药物治疗的患者的心血管不良事件
6. Assessment of the risk of QT-interval prolongation associated with potential drug-drug interactions in patients admitted to Intensive Care Units [O] . Flávia Medeiros Fernandes, Aryelle Mayara da Silva Paulino, Bruna Camelo Sedda, 2019

机译：重症监护病房患者QT间期延长与潜在药物相互作用的风险评估
7. Clinical characteristics and risk factors for in‐hospital mortality of lung cancer patients with COVID ‐19: A multicenter, retrospective, cohort study [O] . Lei Nie, Kai Dai, Jiang Wu, 2020

机译：Covid肺癌患者中医死亡率的临床特征及风险因素-19：多中心，回顾，队列研究

Frequency characteristics and risk factors of QT interval prolonging drugs and drug-drug interactions in cancer patients: a multicenter study

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