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Properties of cellular and serum forms of thymidine kinase 1 (TK1) in dogs with acute lymphocytic leukemia (ALL) and canine mammary tumors (CMTs): implications for TK1 as a proliferation biomarker

机译：急性淋巴细胞白血病（ALL）和犬乳腺肿瘤（CMT）犬的胸苷激酶1（TK1）的细胞和血清形式的特性：TK1作为增殖生物标志物的意义

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BackgroundThymidine kinase 1 (TK1) is a deoxyribonucleic acid (DNA) precursor enzyme and a proliferation biomarker used for prognosis and treatment monitoring of breast cancer in humans. The aim was to determine if serum thymidine kinase 1 (sTK1) activity and sTK1 protein levels in dogs with mammary tumors could be useful in veterinary medicine.

机译：背景胸苷激酶1（TK1）是一种脱氧核糖核酸（DNA）前体酶，是一种增殖生物标志物，用于人类乳腺癌的预后和治疗监测。目的是确定乳腺肿瘤犬的血清胸苷激酶1（sTK1）活性和sTK1蛋白水平是否可用于兽医。

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期刊名称 BMC Veterinary Research
作者
Kiran Kumar Jagarlamudi; Sara Westberg; Henrik Rönnberg; Staffan Eriksson;
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作者单位

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年(卷),期 2014(10),-1
年度 2014
页码 228
总页数 12
原文格式 PDF
正文语种
中图分类动物医学（兽医学）;
关键词
Canine serum thymidine kinase 1 sTK1 protein assays Canine mammary tumors Size exclusion chromatography Anti-dog TK1 antibodies;

机译：犬血清胸苷激酶1;sTK1蛋白测定;犬乳腺肿瘤;尺寸排阻色谱;抗狗TK1抗体;

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1. Properties of cellular and serum forms of thymidine kinase 1 (TK1) in dogs with acute lymphocytic leukemia (ALL) and canine mammary tumors (CMTs): implications for TK1 as a proliferation biomarker [J] . Kiran Kumar Jagarlamudi, Sara Westberg, Henrik R?nnberg, BMC Veterinary Research . 2014,第1期

机译：急性淋巴细胞白血病（ALL）和犬乳腺肿瘤（CMT）犬的胸苷激酶1（TK1）的细胞和血清形式的特性：TK1作为增殖生物标志物的意义
2. Breast and prostate cancer patients differ significantly in their serum Thymidine kinase 1 (TK1) specific activities compared with those hematological malignancies and blood donors: implications of using serum TK1 as a biomarker [J] . Kiran Kumar Jagarlamudi, Lars Olof Hansson, Staffan Eriksson BMC Cancer . 2015,第1期

机译：与血液系统恶性肿瘤和献血者相比，乳腺癌和前列腺癌患者的血清胸苷激酶1（TK1）比活性显着不同：使用血清TK1作为生物标志物的意义
3. A sensitive and kinetically defined radiochemical assay for canine and human serum thymidine kinase 1 (TK1) to monitor canine malignant lymphoma [J] . Sharif H., von Euler H., Westberg S., The Veterinary Journal . 2012,第1期

机译：对犬和人血清胸苷激酶1（TK1）进行敏感性和动力学定义的放射化学测定，以监测犬恶性淋巴瘤
4. MONITORING THERAPY IN CANINE MALIGNANT LYMPHOMA AND LEUKEMIA WITH SERUM THYMIDINE KINASE 1 ACTIVITY - EVALUATION OF A NEW, FULLY AUTOMATED NON-RADIOMETRIC ASSAY [C] . Henrik von Euler, Patricio Rivera, Anne-Charlotte Aronsson, Annual conference of the Veterinary Cancer Society . 2008

机译：监测治疗犬恶性淋巴瘤和白血病患者血清胸苷激酶1活性 - 评价新的，全自动非辐射测定法
5. Overexpression of the receptor tyrosine kinase EphA2 induces malignant transformation of benign mammary epithelia: Implication for increased cell survival and altered cellular adhesions in breast cancer. [D] . Zelinski, Daniel Paul. 2001

机译：受体酪氨酸激酶EphA2的过表达诱导了良性乳腺上皮的恶性转化：暗示增加细胞存活率和改变乳腺癌细胞粘附。
6. Breast and prostate cancer patients differ significantly in their serum Thymidine kinase 1 (TK1) specific activities compared with those hematological malignancies and blood donors: implications of using serum TK1 as a biomarker [O] . Kiran Kumar Jagarlamudi, Lars Olof Hansson, Staffan Eriksson 2015

机译：与血液系统恶性肿瘤和献血者相比乳腺癌和前列腺癌患者的血清胸苷激酶1（TK1）比活性显着不同：使用血清TK1作为生物标志物的意义
7. Properties of cellular and serum forms of thymidine kinase 1 (TK1) in dogs with acute lymphocytic leukemia (ALL) and canine mammary tumors (CMTs): implications for TK1 as a proliferation biomarker [O] . 2014

机译：急性淋巴细胞白血病（ALL）和犬乳腺肿瘤（CMT）犬的胸苷激酶1（TK1）的细胞和血清形式的特性：TK1作为增殖生物标志物的意义

Properties of cellular and serum forms of thymidine kinase 1 (TK1) in dogs with acute lymphocytic leukemia (ALL) and canine mammary tumors (CMTs): implications for TK1 as a proliferation biomarker

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