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Case Report: Liver transplantation for acute liver failure accompanied by severe acute pancreatitis

机译:病例报告:肝移植治疗急性肝功能衰竭伴重症急性胰腺炎

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摘要

The role of liver transplantation (LT) in acute liver failure (ALF) complicated by severe acute pancreatitis is still unclear. We here report a case of deceased-donor LT for idiopathic ALF accompanied by severe acute pancreatitis. A 58-year-old man with no history of liver disease presented with idiopathic ALF and acute pancreatitis. After careful consideration, he received a liver from a deceased donor. Following surgery, the patient's liver function rapidly reverted to normal level and the acute pancreatitis simultaneously subsided. The patient later developed a pancreatic pseudocyst, which was treated successfully with combination interventional radiology. LT can be considered for ALF associated with severe acute pancreatitis if there is no clinical evidence of an absolute contraindication for organ transplantation, such as systemic or local infection. Moreover, we recommend a close follow-up by ultrasonography to allow early detection and treatment of pancreatic pseudocysts following surgery.
机译:肝移植(LT)在并发严重急性胰腺炎的急性肝衰竭(ALF)中的作用仍不清楚。我们在这里报告一例原发性ALF伴有严重急性胰腺炎的死者LT病例。一名无肝病史的58岁男性出现特发性ALF和急性胰腺炎。经过深思熟虑,他从一位已故的捐助者那里得到了肝脏。手术后,患者的肝功能迅速恢复至正常水平,急性胰腺炎同时消退。病人后来发展出了胰腺假性囊肿,并通过联合介入放射学成功治疗。如果没有临床证据表明器官移植有绝对禁忌症,例如全身性或局部感染,则可以考虑将LT用于伴有严重急性胰腺炎的ALF。此外,我们建议通过超声检查密切随访,以便在手术后及早发现和治疗胰腺假性囊肿。

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