A randomized trial assessing the clinical efficacy and microbial eradication of 1 azithromycin ophthalmic solution vs tobramycin in adult and pediatric subjects with bacterial conjunctivitis

摘要

Objective:The study was designed to evaluate the efficacy of an ophthalmic formulation of 1% azithromycin in DuraSite^® (AzaSite™, InSite Vision, Alameda CA, USA) and demonstrate equivalence with 0.3% tobramycin ophthalmic solution, USP, for the treatment of bacterial conjunctivitis as defined by the resolution of clinical signs and the eradication of pathogens.