Plasma levels tissue distribution and excretion of radioactivity after single-dose administration of (3H)-oleic acid added to D-004 a lipid extract of the fruit of Roystonea regia in rats

摘要

Background:D-004, a lipid extract of the fruit of Roystonea regia, contains a mixture of fatty acids—mainly oleic, lauric, palmitic, and myristic acids, with oleic acid being among the most abundant—that has been found to reduce the risk for prostatic hyperplasia (PH) induced with testosterone (T) in rats. The pharmacokinetic profile of D-004 has not been reported.