Objective: To investigate the masseter inhibitory reflex (MIR) and its eventual changes in patients with episodic tension-type headache (TTH). Methods: MIR was studied in 21 patients with episodic TTH and 30 healthy subjects, with age and sex matched to the study cohort. Median age of patients was 17.0 years (ranged 16~49 years), median duration of disease 12 months (1~5 years), and median frequency of headache 7.5 d per month. Results: The second period of suppression (S2) of MIR was reduced in intensity and duration in 10% of controls and 66.7% (confidence interval (CI)=45.3%~85%; P<0.05) of patients with episodic TTH (χ 2=74.9; P<0.001). In 3 (14.3%) of patients with episodic TTH, S2 was completely absent. No significant correlation between the duration of disease and headache frequency was found. Conclusion: Our results confirm the link between episodic TTH and reduction or absence of S2. Teenage patients with episodic TTH may exhibit marked pathological changes in S2 in contrast to older individuals.
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机译：目的：探讨发作性紧张型头痛（TTH）患者的咬肌抑制反射（MIR）及其最终变化。方法：对21名典型的TTH患者和30名健康受试者进行了MIR研究，其年龄和性别与研究对象匹配。患者的中位年龄为17.0岁（范围为16〜49岁），中位病程为12个月（1〜5年），中位头痛的频率为每月7.5 d。结果：发作期TTH（χ2）的MIR抑制的第二阶段（S2）的强度和持续时间减少，分别为10％和66.7％（置信区间（CI）= 45.3％〜85％； P <0.05） 2 = 74.9; P <0.001）。在3例（14.3％）的发作性TTH患者中，S2完全缺失。病程长短与头痛频率之间无显着相关性。结论：我们的结果证实了发作性TTH与S2减少或缺失之间的联系。与年龄较大的个体相比，青少年发作性TTH患者可能在S2中表现出明显的病理变化。
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