Psychosocial Rehabilitation Training in the Treatment of Schizophrenia Outpatients: A Randomized Psychosocial Rehabilitation training–and Monomedication-Controlled Study

摘要

>Objective: This study was designed to evaluate the efficacy of psychosocial rehabilitation intervention on schizophrenia. >Methodology: One hundred forty schizophrenia outpatients in remission stage were randomized to either an antipsychotic monomedication (control group) or an antipsychotic monomedication plus a psychosocial rehabitation training (trial group). Positive and Negative syndrome Scale (PANSS), Disability Screening Schedule (SDSS) were performed longitudinally from baseline to month 18 to evaluate the efficacy. >Results: Significant difference in relapse rate between the control group (42.9%) and the trial group (18.6%) was found at month 18. In patients who didn’t relapse, the trial group showed significantly lower PANSS and SDSS score (P<0.05) than did the control group after treatment. >Conclusion: Psychosocial rehabilitation intervention could produce a better outcome in terms of reducing relapse and improving the social functioning in schizophrenia.