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Evodiamine inactivates NF-κB and potentiates the antitumor effects of gemcitabine on tongue cancer both in vitro and in vivo

机译：Evodiamine使NF-κB失活并增强吉西他滨对舌癌的体内和体外抗肿瘤作用

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摘要

ObjectiveThe aim of this study was to investigate whether evodiamine (EVO) could potentiate the antitumor activity of gemcitabine (GEM) in tongue cancer cells and determine its potential underlying mechanisms.

机译：目的本研究的目的是研究依维他命（EVO）是否能增强吉西他滨（GEM）在舌癌细胞中的抗肿瘤活性，并确定其潜在的潜在机制。

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期刊名称 OncoTargets and therapy
作者
Qi Guo; Yanmei Liu; Jiayuan Zhao; Jing Wang; Yue Li; Yunqing Pang; Jian Chen; Jing Wang;
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作者单位

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年(卷),期 2019(12),-1
年度 2019
页码 257–267
总页数 11
原文格式 PDF
正文语种
中图分类应用微生物学;肿瘤学;
关键词
tongue cancer evodiamine gemcitabine combination index apoptosis NF-κB;

机译：舌癌;依维他明;吉西他滨;联合指数;细胞凋亡;NF-κB;

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专利

1. Evodiamine inactivates NF-κB and potentiates the antitumor effects of gemcitabine on tongue cancer both in vitro and in vivo [J] . Qi Guo, Yanmei Liu, Jiayuan Zhao, OncoTargets and therapy . 2018,第2期

机译：evodiamine灭活NF-κB，增强了吉西他滨对体外和体内舌癌的抗肿瘤作用
2. Dihydroartemisinin inactivates NF-kappaB and potentiates the anti-tumor effect of gemcitabine on pancreatic cancer both in vitro and in vivo. [J] . Wang SJ, Gao Y, Chen H, Cancer letters . 2010,第1期

机译：双氢青蒿素在体外和体内均可灭活NF-κB并增强吉西他滨对胰腺癌的抗肿瘤作用。
3. Maslinic acid potentiates the antitumor activities of gemcitabine in vitro and in vivo by inhibiting NF-kappa B-mediated survival signaling pathways in human gallbladder cancer cells [J] . Yu Yong, Wang Jinghan, Xia Nianxin, Oncology reports . 2015,第4期

机译：山楂酸通过抑制人胆囊癌细胞中的NF-κB介导的生存信号通路来增强吉西他滨的体外和体内抗肿瘤活性。
4. Gemcitabine + Cisplatin Combination Electrochemotherapy for Triple Negative Breast Cancers: An in vitro Model Study [C] . R. Sundararajan, V. Raman, V. Masterson World Congress on Electroporation and Pulsed Electric Fields in Biology, Medicine and Food Environmental Technologies . 2016

机译：Gemcitabine +顺铂组合电化学疗法三重阴性乳腺癌：体外模型研究
5. Inhibition of the NF-κB signaling pathway by the curcumin analogs, 3,5- Bis(2-pyridinylmethylidene)-4-piperidone (EF31) and 3,5-Bis(2- pyridinylmethylidene)-1-methyl-4-piperidone (UBS109): in-vitro and in-vivo studies [D] . Olivera, Anlys 2011

机译：姜黄素类似物3,5-双（2-吡啶基亚甲基）-4-哌啶酮（EF31）和3,5-双（2-吡啶基亚甲基）-1-甲基-4-哌啶酮对NF-κB信号通路的抑制作用（ UBS109）：体外和体内研究
6. Antitumor Activity of Gemcitabine Can Be Potentiated in Pancreatic Cancer through Modulation of TLR4/NF-κB signaling by 6-Shogaol [O] . Ling Zhou, Lianwen Qi, Lifeng Jiang, 2014

机译：吉西他滨的抗肿瘤活性可通过6-Shogaol调节TLR4 /NF-κB信号转导来增强胰腺癌的抗肿瘤活性。
7. Curcumin potentiates the antitumor effects of 5-FU in treatment of esophageal squamous carcinoma cells through downregulating the activation of NF- B signaling pathway in vitro and in vivo [O] . F. Tian, T. Fan, Y. Zhang, 2012

机译：姜黄素增强5-FU在体外和体内激活NF-B信号通路治疗食管鳞状癌细胞的抗肿瘤作用

Evodiamine inactivates NF-κB and potentiates the antitumor effects of gemcitabine on tongue cancer both in vitro and in vivo

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