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Postponing Pregnancy Through Oocyte Cryopreservation for Social Reasons: Considerations Regarding Clinical Practice and the Socio-Psychological and Bioethical Issues Involved

机译:由于社会原因而通过卵母细胞冷冻保存推迟妊娠:关于临床实践以及所涉及的社会心理和生物伦理学问题的考虑

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摘要

Oocyte freezing for ‘social reasons’ refers to women of reproductive age who are aiming to prolong, protect and secure their fertility. The term emerged to describe application of the highly promising technique, namely vitrification on oocytes retrieved through controlled ovarian stimulation (COS) from women intending to preserve their fertility for social reasons. These women opt to cryopreserve their oocytes at a point in their life when they need to postpone childbearing on the grounds of so called ‘social’ reasons. These reasons may include a highly driven career, absence of an adequate partner, financial instability, or personal reasons that make them feel unprepared for motherhood. This is a sensitive and multifaceted issue that entails medical, bioethical and socio-psychological components. The latest trend and the apparent increase noted on oocyte freezing for ‘social reasons’ has prompted our team of fertility specialists, embryologists, obstetricians, gynecologists and psychologists to proceed with a thorough, critical and all-inclusive comprehensive analysis. The wide range of findings of this analysis involve concerns of embryology and epigenetics that shape decisions made in the IVF laboratory, issues regarding obstetric and perinatal concerns on the pregnancy concluding from these oocytes and the respective delivery management and neonatal data, to the social and bioethical impact of this trend’s application. This literature review refers to matters rising from the moment the ‘idea’ of this option is ‘birthed’ in a woman’s thoughts, to proceeding and executing it clinically, up until the point of the pediatric follow up of the children born. We aim to shed light to the controversial issue of oocyte freezing, while objectively exhibit all aspects regarding this complex matter, as well as to respectfully approach how could the prospect of our future expectations be shaped from the impact of its application.
机译:出于“社会原因”而冻结的卵母细胞是指旨在延长,保护和确保生育能力的育龄妇女。出现该术语是为了描述高度有前途的技术的应用,即通过受控卵巢刺激(COS)从打算出于社会原因保留其生育力的妇女的卵母细胞上进行玻璃化。这些妇女选择在他们生命中的某个时刻冷冻卵母细胞,因为她们需要以所谓的“社会原因”推迟生育。这些原因可能包括职业驱动力强,缺乏足够的伴侣,财务不稳定或个人原因,使他们感到自己没有做好孕育的准备。这是一个敏感而多方面的问题,涉及医学,生物伦理和社会心理因素。由于“社会原因”,卵子冻结的最新趋势和明显增加促使我们的生育专家,胚胎学家,妇产科医生,妇科医生和心理学家团队进行了全面,关键和全面的综合分析。该分析的广泛发现涉及胚胎和胚胎遗传学的问题,这些问题影响了体外受精实验室的决策,有关产科和围产期妊娠的问题,包括这些卵母细胞以及各自的分娩管理和新生儿数据,以及对社会和生物伦理的关注。这种趋势的应用的影响。这篇文献综述所涉及的问题,从该选项的“思想”在妇女的思想中“诞生”到临床进行和执行,直至对所生孩子进行儿科随访为止。我们旨在阐明有争议的卵母细胞冷冻问题,同时客观地展示有关这一复杂问题的所有方面,并尊重地探讨如何从其应用的影响中塑造我们未来期望的前景。

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