Effect of CYP2C19 Gene Polymorphisms on Proton Pump Inhibitor Amoxicillin and Levofloxacin Triple Therapy for Eradication of Helicobacter Pylori

机译：CYP2C19基因多态性对质子泵抑制剂阿莫西林和左氧氟沙星三联疗法根除幽门螺杆菌的影响

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BackgroundThe effects of PPI are variable owing to the CYP2C19 polymorphisms. However, whether the polymorphisms could affect the Hp eradication efficacy of triple therapy is still not clear. The present study aimed to assess the effects of CYP2C19 gene polymorphisms on proton pump inhibitor (PPI), amoxicillin, and levofloxacin triple therapy for Helicobacter pylori (Hp) eradication.

机译：背景由于CYP2C19多态性，PPI的影响是可变的。然而，多态性是否会影响三联疗法根除Hp的疗效尚不清楚。本研究旨在评估CYP2C19基因多态性对根除幽门螺杆菌（Hp）的质子泵抑制剂（PPI），阿莫西林和左氧氟沙星三联疗法的影响。

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期刊名称 Medical Science Monitor : International Medical Journal of Experimental and Clinical Research
作者
Yun-An Lin; Hong Wang; Zhu-Jun Gu; Wen-Jia Wang; Xiao-Yan Zeng; Yan-Lei Du; Song-Song Ying; Bo-Hua Zhang;
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作者单位

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年(卷),期 2017(23),-1
年度 2017
页码 2701–2707
总页数 7
原文格式 PDF
正文语种
中图分类
关键词
Amoxicillin Helicobacter pylori Levofloxacin Proton Pump Inhibitors;

机译：阿莫西林;幽门螺杆菌;左氧氟沙星;质子泵抑制剂;

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专利

1. Effect of CYP2C19 Genetic Polymorphisms on the Efficacy of Proton Pump Inhibitor-Based Triple Therapy for Helicobacter pylori Eradication: A Meta-Analysis [J] . Zhao FJ, Wang J, Yang YM, Helicobacter . 2008,第6期

机译：CYP2C19基因多态性对基于质子泵抑制剂的幽门螺杆菌根除三联疗法疗效的荟萃分析
2. Effect of the CYP2C19 polymorphism on the eradication rate of Helicobacter pylori infection by 7-day triple therapy with regular proton pump inhibitor dosage. [J] . Kang JM, Kim N, Lee DH, Journal of gastroenterology and hepatology . 2008,第8aPta1期

机译：CYP2C19基因多态性对7天三联疗法（常规质子泵抑制剂剂量）对幽门螺杆菌感染根除率的影响。
3. Efficacy of the standard quadruple therapy versus triple therapies containing proton pump inhibitor plus amoxicillin and clarithromycin or amoxicillin-clavulanic acid and metronidazole for Helicobacter pylori eradication in children. [J] . Dehghani SM, Erjaee A, Imanieh MH Digestive Diseases and Sciences . 2009,第8期

机译：标准四联疗法与含质子泵抑制剂加阿莫西林和克拉霉素或阿莫西林-克拉维酸和甲硝唑的三联疗法在儿童幽门螺杆菌根除中的疗效。
4. Development of Mucoadhesive Microparticle of Amoxicillin for anti-Helicobacter Pylori Therapy by Supercritical Assisted Atomization Technique [C] . Jawadan K. Patel, Priyanka S. Patil Annual meeting exposition of the Controlled Release Society . 2010

机译：超临界辅助雾化技术开发阿莫西林粘膜粘附微粒抗幽门螺杆菌治疗
5. Secondary analysis of effectivness of tinidazole-containing-quadruple eradication therapy in asymptomatic Helicobacter pylori infected children in El Paso [D] . Prieto-Jimenez, Carmen Aida 2010

机译：EL Pyliancational幽门螺杆菌幽门螺杆菌幽门术中含锡咪唑类含有四肢切除治疗的有效性的二次分析
6. Proton pump inhibitor-amoxicillin-clarithromycin versus proton pump inhibitor-amoxicillin-metronidazole as first-line Helicobacter pylori eradication therapy [O] . Toshihiro Nishizawa, Hidekazu Suzuki, Masayuki Suzuki, 2012

机译：质子泵抑制剂-阿莫西林-克拉霉素与质子泵抑制剂-阿莫西林-甲硝唑作为一线幽门螺杆菌根除疗法
7. Efficacy of triple therapy with a proton pump inhibitor, levofloxacin, and amoxicillin as first-line treatment to eradicate helicobacter pylori [O] . Pérez Pastor Ángeles, Romero Gómez Manuel, Vargas Romero Julio, 2009

机译：质子泵抑制剂，左氧氟沙星和阿莫西林作为根除幽门螺杆菌的一线治疗三联疗法的疗效

Effect of CYP2C19 Gene Polymorphisms on Proton Pump Inhibitor Amoxicillin and Levofloxacin Triple Therapy for Eradication of Helicobacter Pylori

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