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Insights into the molecular mechanism of glucose metabolism regulation under stress in chicken skeletal muscle tissues

机译:鸡骨骼肌组织在应激条件下葡萄糖代谢调控的分子机制研究

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摘要

As substantial progress has been achieved in modern poultry production with large-scale and intensive feeding and farming in recent years, stress becomes a vital factor affecting chicken growth, development, and production yield, especially the quality and quantity of skeletal muscle mass. The review was aimed to outline and understand the stress-related genetic regulatory mechanism, which significantly affects glucose metabolism regulation in chicken skeletal muscle tissues. Progress in current studies was summarized relevant to the molecular mechanism and regulatory pathways of glucose metabolism regulation under stress in chicken skeletal muscle tissues. Particularly, the elucidation of those concerned pathways promoted by insulin and insulin receptors would give key clues to the understanding of biological processes of stress response and glucose metabolism regulation under stress, as well as their later effects on chicken muscle development.
机译:近年来,随着现代家禽生产的大规模和集约化饲喂和耕种取得了实质性进展,压力已成为影响鸡的生长,发育和生产产量(尤其是骨骼肌质量和数量)的重要因素。这篇综述旨在概述和理解与压力相关的遗传调节机制,该机制显着影响鸡骨骼肌组织中的葡萄糖代谢调节。总结了当前研究的进展与鸡骨骼肌组织在应激条件下葡萄糖代谢调控的分子机制和调控途径有关。特别地,阐明由胰岛素和胰岛素受体促进的那些相关途径将为理解应激下应激反应和葡萄糖代谢调节的生物学过程及其对鸡肌肉发育的后期影响提供关键线索。

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