A novel model to correlate hydrogel spacer placement perirectal space creation and rectum dosimetry in prostate stereotactic body radiotherapy

摘要

BackgroundThe SpaceOAR hydrogel is employed to limit rectal radiation dose during prostate radiotherapy. We identified a novel parameter – the product of angle θ and hydrogel volume – to quantify hydrogel placement. This parameter predicted rectum dosimetry and acute rectal toxicity in prostate cancer patients treated with stereotactic body radiotherapy to 36.25 Gy in 5 fractions.