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Low body mass index and old age are useful in predicting the hemoglobin A1c-lowering effect of switching from sitagliptin to dulaglutide in Japanese patients with type 2 diabetes mellitus: a single-center open-label single-arm pilot study

机译：低体重指数和高龄有助于预测日本2型糖尿病患者从西他列汀转为dulaglutide降低血红蛋白A1c的作用：单中心开放标签单组前瞻性研究

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摘要

AimsThe purpose of this study was to clarify the predictive clinical characteristics of therapy switching from sitagliptin to dulaglutide in patients with type 2 diabetes mellitus.

机译：目的本研究的目的是阐明2型糖尿病患者从西他列汀转为dulaglutide的治疗的预测临床特征。

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期刊名称 Diabetology international
作者
Tomoyuki Iwasaki; Takaomi Kessoku; Takuma Higurashi; Masataka Taguri; Masato Yoneda;
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作者单位

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年(卷),期 2018(9),3
年度 2018
页码 189–195
总页数 7
原文格式 PDF
正文语种
中图分类
关键词
Type 2 diabetes mellitus Dulaglutide Sitagliptin Glucagon-like peptide-1 receptor agonist Predictive clinical characteristics;

机译：2型糖尿病;杜拉鲁肽;西他列汀;胰高血糖素样肽1受体激动剂;预测性临床特征;

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专利

1. Population pharmacodynamic analysis of hemoglobin A1c-lowering effects by adding treatment of DPP-4 inhibitors (sitagliptin) in type 2 diabetes mellitus patients based on electronic medical records [J] . Makoto Kakara, Hiroko Nomura, Mai Ezaki, Journal of diabetes and its complications . 2016,第7期

机译：基于电子医疗记录
2. Both glimepiride and high-dose metformin are important for sustained glucose lowering in japanese type 2 diabetes patients on glimepiride- sitagliptin-metformin therapy: Subanalysis of a single-center, open-label, randomized study [J] . AraiK., MaedaH., ShirabeS.-I., Diabetes technology & therapeutics . 2014,第7期

机译：格列美脲-西他列汀-二甲双胍治疗对格列吡脲和西他列汀-二甲双胍治疗的日本2型糖尿病患者而言，格列美脲和大剂量二甲双胍均对持续降低血糖很重要：单中心，开放标签，随机研究的亚分析
3. Safety and efficacy of canagliflozin in Japanese patients with type 2 diabetes mellitus: post hoc subgroup analyses according to body mass index in a 52-week open-label study [J] . Nobuya Inagaki, Maki Goda, Shoko Yokota, Expert opinion on pharmacotherapy . 2015,第11期

机译：羊皮脂素在日本型糖尿病患者中的安全性和有效性：在52周的开放标签研究中根据体重指数进行HOC亚组分析
4. A series of open-label studies comparing various formulations of orally administeredinsulin (Oralin) in patients with Type -1 Diabetes Mellitus (DM) [C] . Jaime Guevara-Aguirre, Marco Guevara, Jeannette Saavedra Annual meeting exposition of the Controlled Release Society . 2005

机译：一系列开放标签研究比较了-1型糖尿病（DM）患者口服胰岛素（Oralin）的各种配方
5. Baseline low-density lipoprotein cholesterol predicts the hemoglobin A1c-lowering effect of dapagliflozin in Japanese patients with type 2 diabetes mellitus [O] . Tomoyuki Iwasaki, Masato Yoneda 2016

机译：基线低密度脂蛋白胆固醇可预测dapagliflozin对日本2型糖尿病患者的血红蛋白A1c降低作用
6. Baseline low-density lipoprotein cholesterol predicts the hemoglobin A1c-lowering effect of dapagliflozin in Japanese patients with type 2 diabetes mellitus [O] . Tomoyuki Iwasaki, Masato Yoneda 2015

机译：基线低密度脂蛋白胆固醇预测Dapagliflozin在日本2型糖尿病患者中的血红蛋白A1C降低效果

Low body mass index and old age are useful in predicting the hemoglobin A1c-lowering effect of switching from sitagliptin to dulaglutide in Japanese patients with type 2 diabetes mellitus: a single-center open-label single-arm pilot study

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