Influence of exposure differences on city-to-city heterogeneity in PM2.5-mortality associations in US cities

摘要

BackgroundMulti-city population-based epidemiological studies have observed heterogeneity between city-specific fine particulate matter (PM2.5)-mortality effect estimates. These studies typically use ambient monitoring data as a surrogate for exposure leading to potential exposure misclassification. The level of exposure misclassification can differ by city affecting the observed health effect estimate.