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Differences in the epigenetic and reprogramming properties of pluripotent and extra-embryonic stem cells implicate chromatin remodelling as an important early event in the developing mouse embryo

机译：多能干和胚外干细胞的表观遗传和重编程特性的差异暗示着染色质重塑是小鼠胚胎发育中的重要早期事件

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BackgroundDuring early mouse development, two extra-embryonic lineages form alongside the future embryo: the trophectoderm (TE) and the primitive endoderm (PrE). Epigenetic changes known to take place during these early stages include changes in DNA methylation and modified histones, as well as dynamic changes in gene expression.

机译：背景在小鼠早期发育过程中，两个胚胎外谱系与未来的胚胎一起形成：滋养外胚层（TE）和原始内胚层（PrE）。已知在这些早期阶段发生的表观遗传变化包括DNA甲基化和修饰的组蛋白变化，以及基因表达的动态变化。

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期刊名称 Epigenetics Chromatin
作者
Joana Santos; C Filipe Pereira; Aida Di-Gregorio; Thomas Spruce; Olivia Alder; Tristan Rodriguez; Véronique Azuara; Matthias Merkenschlager; Amanda G Fisher;
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年(卷),期 2010(3),-1
年度 2010
页码 1
总页数 12
原文格式 PDF
正文语种
中图分类遗传学;
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专利

1. Differences in the epigenetic and reprogramming properties of pluripotent and extra-embryonic stem cells implicate chromatin remodelling as an important early event in the developing mouse embryo [J] . Joana Santos, C Filipe Pereira, Aida Di-Gregorio, Epigenetics & Chromatin . 2010,第1期

机译：多能干和胚外干细胞表观遗传和重编程特性的差异表明染色质重塑是小鼠胚胎发育中的重要早期事件
2. A minimal ubiquitous chromatin opening element (UCOE) effectively prevents silencing of juxtaposed heterologous promoters by epigenetic remodeling in multipotent and pluripotent stem cells [J] . Mueller-Kuller Uta, Ackermann Mania, Kolodziej Stephan, Nucleic Acids Research . 2015,第3期

机译：最小普遍的染色质开口元件（UCoE）有效地通过多能和多能干细胞中的表观遗传重塑沉淀并置异源启动子沉默
3. A minimal ubiquitous chromatin opening element (UCOE) effectively prevents silencing of juxtaposed heterologous promoters by epigenetic remodeling in multipotent and pluripotent stem cells [J] . Mueller-Kuller Uta, Ackermann Mania, Kolodziej Stephan, Nucleic Acids Research . 2015,第3期

机译：最小的普遍存在的染色质开放元件（UCOE）通过在多能和多能干细胞中进行表观遗传重塑，有效防止了并列异源启动子的沉默
4. Activation of Hematopoiesis and Vasculogenesis in the Mouse Embryo: Induction and Reprogramming of Ectodermal Cell Fate by Signals from Primitive Endoderm [C] . Margaret H. Baron Symposium on Structures and Mechanisms: from Ashes to Enzymes, May 12-14, 2000 . 2000

机译：小鼠胚胎中造血功能和血管生成的激活：原始内胚层的信号诱导和重编程外胚层细胞的命运
5. The Generation of Induced Pluripotent Stem Cell by Recombinant Proteins, and The Essential Epigenetic Role of Jak/Stat3 in Promoting Murine Somatic Cell Reprogramming. [D] . Tang, Yong. 2012

机译：重组蛋白诱导多能干细胞的产生，以及Jak / Stat3在促进小鼠体细胞重编程中的基本表观遗传学作用。
6. A minimal ubiquitous chromatin opening element (UCOE) effectively prevents silencing of juxtaposed heterologous promoters by epigenetic remodeling in multipotent and pluripotent stem cells [O] . Uta Müller-Kuller, Mania Ackermann, Stephan Kolodziej, 2015

机译：最小的普遍存在的染色质开放元件（UCOE）通过在多能和多能干细胞中进行表观遗传重塑有效防止了并列异源启动子的沉默
7. Differences in the epigenetic and reprogramming properties of pluripotent and extra-embryonic stem cells implicate chromatin remodelling as an important early event in the developing mouse embryo [O] . Santos Joana, Filipe Pereira C, Di-Gregorio Aida, 2010

机译：多能干和胚外干细胞的表观遗传和重编程特性的差异暗示着染色质重塑是小鼠胚胎发育中的重要早期事件

Differences in the epigenetic and reprogramming properties of pluripotent and extra-embryonic stem cells implicate chromatin remodelling as an important early event in the developing mouse embryo

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