Impairment in Respiratory Function Contributes to Olfactory Impairment in Amyotrophic Lateral Sclerosis

摘要

BackgroundNonmotor symptoms are very common in neurodegenerative diseases. In patients suffering from amyotrophic lateral sclerosis (ALS), olfactory dysfunction was first reported more than 20 years ago; however, its pathophysiological correlates and further implications remain elusive.