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IBCs 22nd Annual Antibody Engineering and 9th Annual Antibody Therapeutics International Conferences and the 2011 Annual Meeting of The Antibody Society December 5–8 2011 San Diego CA

机译:IBC第22届年度抗体工程和第9届年度抗体治疗国际会议以及2011年抗体学会年会2011年12月5日至8日加利福尼亚州圣地亚哥

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摘要

The 22nd Annual Antibody Engineering and 9th Annual Antibody Therapeutics international conferences, and the 2011 Annual Meeting of The Antibody Society, organized by IBC Life Sciences with contributions from The Antibody Society and two Scientific Advisory Boards, were held December 5–8, 2011 in San Diego, CA. The meeting drew ∼800 participants who attended sessions on a wide variety of topics relevant to antibody research and development. As a preview to the main events, a pre-conference workshop held on December 4, 2011 focused on antibodies as probes of structure. The Antibody Engineering Conference comprised eight sessions: (1) structure and dynamics of antibodies and their membrane receptor targets; (2) model-guided generation of binding sites; (3) novel selection strategies; (4) antibodies in a complex environment: targeting intracellular and misfolded proteins; (5) rational vaccine design; (6) viral retargeting with engineered binding molecules; (7) the biology behind potential blockbuster antibodies and (8) antibodies as signaling modifiers: where did we go right, and can we learn from success? The Antibody Therapeutics Conference comprised five sessions: (1) Twenty-five years of therapeutic antibodies: lessons learned and future challenges; (2) preclinical and early stage development of antibody therapeutics; (3) next generation anti-angiogenics; (4) updates of clinical stage antibody therapeutics and (5) antibody drug conjugates and bispecific antibodies.
机译:由IBC Life Sciences组织,由抗体学会贡献的第22届年度抗体工程和第9届年度抗体治疗国际会议,以及2011年抗体学会年会和两个科学顾问委员会,分别于2011年12月5日至8日在加利福尼亚州圣地亚哥举行。该会议吸引了约800名参与者,他们参加了与抗体研发相关的各种主题的会议。作为主要活动的预览,2011年12月4日举行的会前研讨会重点讨论了抗体作为结构探针。抗体工程会议包括八个部分:(1)抗体及其膜受体靶的结构和动力学; (2)模型指导的结合位点的产生; (3)新颖的选拔策略; (4)复杂环境中的抗体:靶向细胞内和错误折叠的蛋白质; (5)合理的疫苗设计; (6)用工程结合分子进行病毒靶向; (7)潜在的重磅炸弹抗体背后的生物学原理,以及(8)作为信号转导修饰剂的抗体:我们在哪里走对了,我们可以从成功中学到什么?抗体治疗学会议包括五届会议:(1)治疗性抗体二十五年:经验教训和未来挑战; (2)抗体治疗剂的临床前和早期开发; (3)下一代抗血管生成药; (4)临床阶段抗体疗法的更新以及(5)抗体药物偶联物和双特异性抗体。

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