首页> 美国卫生研究院文献>Indian Journal of Otolaryngology and Head Neck Surgery >Comparing the Efficacy of Alkaline Nasal Douches Versus Decongestant Nasal Drops in Postoperative Care After Septal Surgery: A Randomised Single Blinded Clinical Pilot Study
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Comparing the Efficacy of Alkaline Nasal Douches Versus Decongestant Nasal Drops in Postoperative Care After Septal Surgery: A Randomised Single Blinded Clinical Pilot Study

机译:鼻中隔手术后碱性鼻腔冲洗与鼻腔充血鼻腔滴注的比较:随机单盲临床试验研究

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摘要

To compare the efficacy of alkaline nasal douches and decongestant nasal drops following nasal septal surgery. This was a prospective, randomised, single-blind pilot study. Twenty patients were included in each arm of the study undergoing elective nasal septal surgery. The primary outcome measure was nasal congestion. Secondary outcome measures were anosmia, facial pain, nasal discharge, and sneezing/itching. This study does not show any statistically significant difference between the two treatment groups. Symptoms of nasal congestion (P = 0.3), facial pain (P = 0.932), nasal discharge (P = 0.98), sneezing (P = 0.59) and anosmia (P = 0.208) were analysed before conclusion. Three patients in saline group and one patient in the nasal drops group had poor compliance to follow the advice, scoring 2 on a VAS score but the treatment was tolerated well in majority of the patients. No statistical significant differences were noted on analysing the post operative complications in either group. In this study, both nasal douches and decongestant nasal drop were well tolerated. Both treatments provided good postoperative relief from nasal congestion, nasal discharge, sneezing, facial pain and anosmia as days progressed. The post operative examination of the nose among these patients revealed no significant complications in either of the study arm.
机译:比较鼻中隔手术后碱性鼻腔冲洗液和充血性滴鼻剂的疗效。这是一项前瞻性,随机,单盲试验研究。该研究的每一臂中均包括20名接受鼻中隔手术的患者。主要结果指标是鼻塞。次要结果指标是失眠,面部疼痛,鼻涕和打喷嚏/痒。这项研究没有显示两个治疗组之间的任何统计学显着差异。在得出结论之前,先分析了鼻充血(P = 0.3),面部疼痛(P = 0.932),鼻分泌物(P = 0.98),打喷嚏(P = 0.59)和失眠(P = 0.208)的症状。盐水组中的3例患者和滴鼻剂组中的1例患者遵循建议的依从性差,在VAS评分上得分2,但大多数患者对治疗的耐受性良好。两组的术后并发症分析均无统计学差异。在这项研究中,鼻腔冲洗液和充血性鼻滴液的耐受性都很好。随着日间的发展,这两种治疗方法都可为术后的鼻充血,流鼻涕,打喷嚏,面部疼痛和失眠提供良好的术后缓解。在这些患者中,对鼻子进行术后检查后发现,任何一个研究组均无明显并发症。

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