首页> 美国卫生研究院文献>Immunology >Studies on the mechanism of macrophage aggregation induced by lymphokines.
【2h】

Studies on the mechanism of macrophage aggregation induced by lymphokines.

机译:淋巴因子诱导巨噬细胞聚集的机制研究。

代理获取
本网站仅为用户提供外文OA文献查询和代理获取服务,本网站没有原文。下单后我们将采用程序或人工为您竭诚获取高质量的原文,但由于OA文献来源多样且变更频繁,仍可能出现获取不到、文献不完整或与标题不符等情况,如果获取不到我们将提供退款服务。请知悉。

摘要

Macrophage aggregation (measured by a light-scattering technique) induced by unpurified lymphokine preparations has been investigated. This has been shown to be Ca2+ or Mg2+ dependent and to be inhibited by a number of agents known to affect cellular physiology and biochemistry. The divalent cation ionophore A23187 causes a macrophage aggregation superficially similar to that induced by lymphokines, although differences were found. It is suggested that a biochemical response by the macrophage is required for aggregation induced by lymphokines, and thus measurements of macrophage aggregation allow a study of the early events in the response of macrophages to lymphokines.
机译:已研究了未经纯化的淋巴因子制剂引起的巨噬细胞聚集(通过光散射技术测量)。已经证明这是Ca 2+或Mg 2+依赖性的,并被许多已知会影响细胞生理学和生物化学的试剂所抑制。尽管发现差异,但是二价阳离子离子载体A23187引起的巨噬细胞聚集表面上类似于淋巴因子诱导的聚集。有人提出,巨噬细胞的生化反应是淋巴因子诱导的聚集所必需的,因此对巨噬细胞聚集的测量可以研究巨噬细胞对淋巴因子应答的早期事件。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
代理获取

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号