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Phyllodes Tumor in a Lactating Breast

机译:泌乳性乳腺肿瘤

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摘要

Phyllodes tumor is attributed to a small fraction of primary tumors of the breast. Such tumors occur rarely in pregnancy and lactation. We report a case of a 25-year-old lactating mother presenting with a lump in the left breast. Core needle biopsy was opined as phyllodes tumor with lactational changes, and subsequent wide local excision confirmed the diagnosis of benign phyllodes tumor with lactational changes. The characteristic gross and microscopic findings of a well-circumscribed lesion with leaf-like fibroepithelial growth pattern and typical nonuniform or diffuse stromal proliferation with periductal accentuation even in the absence of mitotic figures can help clinch the diagnosis. Benign phyllodes is known for its recurrence and requires wide excision and close follow-up. It is vital to identify these lesions even on limited biopsies as therapeutic options differ. This case is presented for its rarity and the diagnostic challenge it poses in limited biopsy.
机译:毛状细胞瘤归因于乳腺原发性肿瘤的一小部分。这种肿瘤很少在怀孕和哺乳期发生。我们报告了一例25岁的哺乳期母亲左乳房肿块。核心针穿刺活检被认为是乳头状肿瘤伴乳汁性改变,随后广泛的局部切除证实了乳腺良性叶状瘤伴乳汁性改变的诊断。即使是在没有有丝分裂的情况下,具有良好边界的病灶(具有叶状纤维上皮生长模式和典型的不均匀或弥漫性基质增生,并伴有导管周围强化)的特征性肉眼和镜下发现也可以帮助诊断。良性叶状癌因其复发而闻名,需要广泛切除和密切随访。由于治疗选择的不同,即使在有限的活检中也要鉴别这些病变,这一点至关重要。本病例因其稀有性和有限的活检所带来的诊断挑战而被提出。

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