cqvip:A Danish clinical trial showed that transfusion with leucocyte- depleted red blood cells reduces postoperative infectious complications compared with cells without buffy- coat. However, the effect on long- term outcome is unknown. We followed up the 142 cancer patients transfused with buffy- coat- poor red cell s, the 118 transfused with leucocyte- depleted blood, and the 329 who were not transfused, until 2003. After 7 years’ follow- up, survival for those with leucocyte- depleted blood transfusion (46 [41% ]) was not significantly dif ferent from transfusion of blood without buffy- coat (59 [45% ], p=0.51). Alth ough survival is reduced by blood transfusion, it does not differ between the tw o transfusion regimens.
展开▼
