PURPOSE:To compare inter-eye patterns of visual field(VF)-loss on standard automated perimetry(SAP)in patients with glaucomatous optic neuropathy.DESIGN:Observational cross-sectional study.METHODS:Four-hundred-and-ninety eyes of 245 patients with glaucomatous optic neuropathy in at least one eye defined by masked stereophoto review were included.Patients had two reliable SAP visual fields within fifteen months for each eye.Patterns of visual field loss were classified independently by two graders masked to all other patient information.Patterns were described as altitudinal,arcuate,partial arcuate,paracentral,nasal step,temporal wedge,or normal based on the classification system of Keltner and associates.Superior and inferior hemifields were graded separately.RESULTS:Inter-grader agreement in visual field patterns before adjudication was 97% and 94% for the worse eye(superior and inferior hemifield)and 97% and 95% for the better eye(superior and inferior hemifield).The percentage of correspondence by hemifield location was:53%(superiorsuperior),62%(inferior-inferior),45%(superior-inferior),and 55%(inferior-superior).The highest correspondence of individual glaucomatous VF pattern between eyes was for arcuate(superior-superior)and inferior partial arcuate(inferior-inferior)defects(24% and 26%,respectively).Smaller hemifield patterns showed lower correspondence between the eyes(nasal step,paracentral,temporal wedge,0% to 13% correspondence).CONCLUSIONS:Patterns of visual field loss between eyes often corresponded within the same VF hemifield(superior-superior,inferior-inferior)as well as between opposite hemifields(inferior-superior),although opposite hemifield correspondence was less common.More advanced visual field defects(for example,partial arcuate)showed higher correspondence rates between the eyes than less advanced defects.
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