Objective: The purpose of this study was to determine the relationship between nocturia and obstructive sleep apnea (OSA),and the effect of continuous positive airways pressure (CPAP)- therapy on nocturic frequency. Study design: This was a retrospective review of sleep studies including patients with and without evidence of OSA, before and during CPAP treatment(where relevant). Chi-squared tests compared nocturia prevalence according to sleep diagnosis, logistic regression determined predictors of nocturia, and regression analyses determined predictors of nocturic frequency. Results: In 196 eligible studies, predictors of nocturia included increasing age and diabetes mellitus; nocturia was equally likely to occur in patients with and without OSA. In patients with OSA and nocturia,nocturic frequency was related to age, diabetes, and severity of OSA (P < .001). Patients with OSA and nocturia who were treated with CPAP demonstrated a significant decrease in nocturic frequency (P < .001). Conclusion: OSA severity predicts nocturic frequency. The role of testing in the triage of patients with nocturia remains to be determined.
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