204例ALI／ARDS患者脏腑证候分布及肺肠相关特征的临床调查

摘要

目的：通过急性肺损伤/急性呼吸窘迫综合征（ALI/ARDS ）证候分布及肺与大肠证候关联特征的临床调查，为阐释该病病机特点，制定有效的临床救治方案提供理论依据。方法：采用临床流行病学横断面调查的方法，收集204例ALI/ARDS患者四诊信息，按照证候要素提取的思路判断各脏腑证候类型，采用频数分布和相关分析方法分析研究数据。结果：ALI/ARDS证候分布表现出了多脏腑累及的特征；脏腑证候中肺、肠证候具有明显相关性，具体表现为肺气虚与肠热腑实显著相关，痰热壅盛证与肠热腑实、肠燥津亏显著相关。结论：阐明ALI/ARDS脏腑证候分布及肺肠相关特征，进一步加深对ALI/ARDS证候表现及肺与大肠相关性的认识，为临床治疗提供思路。%Objective:To investigate the distribution of Zang-Fu syndromes and characteristics of“exterior-exterior ration of lung and large intestine”in acute lung injury and acute respiratory distress syndrome (ALI/ARDS)so as to provide theoretical evidence to estab-lishing effective clinical treatment protocol.Methods:Clinical epidemiology cross-sectional survey method was used to collect the clini-cal symptoms of 204 patients with ALI/ARDS.Distinguish syndrome based on Syndrome factors.Frequency distribution and correlation analysis methods were used to analyze the research data.Results:ARDS syndromes distribution involved lung,heart,liver,spleen, kidney and large intestine,showing involving characteristics of many viscera syndromes.In viscera syndromes,lung and intestine syn-dromes had obvious correlation,and the specific performance was that lung-qi deficiency syndrome was positively correlated with syn-drome of bowel heat and repletion.The syndrome of phlegm heat obstruction was significantly correlated with syndrome of bowel heat and repletion and intestine-dryness.Conclusion:Exploring lung and large intestine syndrome distribution and the correlation feature can be used to profoundly understand the theory of“exterior-exterior ration of lung and large intestine”and provide the theoretic basis for clini-cal treatment.