基于 AMPK 的中药有效成分治疗2型糖尿病的研究进展

摘要

腺苷酸活化蛋白激酶（ AMP-activated Protein Kinase ，AMPK）在调节细胞和全身代谢中发挥着重要作用，是研究治疗2型糖尿病药物的关键靶点。本文介绍了AMPK的结构及调节方式，并通过检索文献，对通过调节AMPK及其相关信号通路干预2型糖尿病的中药有效成分进行归纳总结。%The AMP-activated protein kinase ( AMPK) is a key senor in cellular and systematic metabolism , and has become a key target in research of anti-diabetic drugs .This article is to introduce the structure and regulation mechanism of the AMPK .By literature searching , it is to summarize research progress on traditional Chinese medicine in the treatment of type 2 diabetes based on the AMP-activated protein kinase and related signaling pathway .