中西药物联用对老年高血压合并2型糖尿病患者肾功能的保护作用

摘要

目的:探讨氯沙坦、硝苯地平控释片、六味地黄丸联用对老年高血压合并2 型糖尿病患者肾功能的保护作用.方法:采用氯沙坦、硝苯地平控释片、六味地黄丸联合治疗老年高血压合并2 型糖尿病患者,观察治疗前后患者血压、血糖、肾功能等指标的变化情况.结果:血压及血糖水平治疗前后相比,差异有统计学意义(P＜0.05);肾功能各指标治疗后优于治疗前,差异有统计学意义(P＜0.05).结论:在常规降糖治疗的基础上,氯沙坦和硝苯地平控释片、六味地黄丸联用能有效控制血压,同时起到保护肾功能的作用.%Objective: To explorethe the protection of losartan, nifedipine controlled-release tablets and LiuWei DiHuangWan on renal function of patients with senile hypertension and type 2 diabetes mellitus. Method: Patients with senile hypertension and type 2 diabetes mellitus were treated with losartan, nifedipine controlled-release tablets and LiuWei DiHuangWan, Changes including blood pressure, blood glucose, renal function and others were observed before and after treating. Result: Comparisons before and after treating had differences with statistical meaning in blood pressure and blood glucose(P<0.05). Indexes of renal function after treating were superior to that before treating and comparisons showed statistical meaning (P<0.05). Conclusion: On the basis of routine glucose-lowering treatment, combination of losartan, nifedipine controlled-release tablets and LiuWei DiHuangWan can effectively control blood pressure and protect renal function.