四妙永安汤加味治疗急性痛风性关节炎140例

摘要

目的:观察四妙永安汤加减治疗急性痛风性关节炎的临床疗效.方法:将140 例急性痛风性关节炎患者随机分为2 组.治疗组70 例,予四妙永安汤加减;对照组70 例,予秋水仙碱、苯溴马隆治疗,2 组疗程均为2 周.观察治疗前后病变关节肿胀、疼痛、活动等情况及血尿酸、血沉和C 反应蛋白的变化情况.结果:治疗组与对照组总有效率分别为88.57%、74.29%,不良反应发生率分别为21.43%、58.57%,2组比较有显著性差异(P＜0.05).结论:四妙永安汤加减治疗急性痛风性关节炎疗效显著,不良反应发生率较低.%Objective: To observe clinical effects of modified SiMiao YongAnTang in treating acute gouty arthritis. Method: All 140 cases were randomly assigned into treatment group administered with modified SiMiao YongAnTang and control group treated with colchicines and benzbromarone. The session was two weeks for both groups. The conditions of joint swelling, pain, movement and the changes of blood uric acid, erythrocyte sedimentation rate and C reactive protein were observed before and after the treatment. Result: Total effective rate of treatment group was 88.57%, higher than 74.29% of control group with significant difference (P<0.05). Incidence of adverse reaction of treatment group was 21.43%,lower than 58.57% of control group with statistical meaning (P<0.05).Conclusion: Modified SiMiao YongA nTang is effective in treating acute gouty arthritis with low incidence of adverse reaction.