长期住院精神分裂症患者伴发代谢综合征情况及相关因素分析

摘要

目的：了解长期住院精神分裂症患者中代谢综合征（ MS）检出率及其相关影响因素。方法选取在惠州市第二人民医院住院时间≥6月、符合《国际疾病分类（第10版）》（ICD-10）诊断标准的683例精神分裂症患者为研究对象。收集社会人口学资料、病史、药物使用情况，测量体重、身高、腹围和血压，实验室检查血糖、血脂等指标。结果683例精神分裂症患者中，伴MS有192例（28.1%）。其中男性111例（23%），女性81例（33.1%）。病程≥5年者138例（30.9%），病程<5年者54例（22.8%），差异均有统计学意义（P均<0.05）。体重指数、甘油三酯、血压在不同性别间差异有统计学意义（P<0.05）。结论长期住院精神分裂症患者中女性和病程≥5年可能是MS的危险因素。%Objective To understand the long-term hospitalization detection rate and related factors of metabolic syndrome in patients with schizophrenia. Methods 683 cases of schizophrenia patients met the diagnosis of schizophrenia of ICD-10 were sele cted in the second peopleˊs hospital of Huizhou. Collecting social demographic data,medical history,drug usage,meas-uring weight and height,blood pressure and laboratory examination indexes of blood sugar,blood fat. Results 683 cases of schizophrenia,with MS 192 cases(28. 1%),and 111 cases(23%)of men,81 cases(33. 1%)of women. There are 138 cases(30. 9%)whose course was more than 5 years,and 54 cases(22. 8%)less than 5 years. The difference was statistical signifi-cant(P<0. 05). The difference of body mass index(BMI),triglycerides,blood pressure between different gender was statistically significant(P<0. 05). Conclusion Long-term hospitalized patients with schizophrenia in women and a course of 5 years or more may be a risk factor for MS.