目的 探讨原发性乳腺恶性淋巴瘤(PBL)的诊断方法及病理特征和预后.方法 从2001年1月～2011年12月,对19例我院手术治疗并经过病理确诊的PBL患者临床病理资料及随访结果进行回顾性分析；计算其术后1、3和5年生存时间.结果 全部患者均为术后病理及免疫组化确诊.按Abor分期标准:Ⅰ期9例、Ⅱ期7例、Ⅲ期3例.11例行肿块局部切除术,4例行单乳切除或区段切除术加腋窝淋巴结清扫,4例行改良根治术；19例均接受化疗,其中7例联合放疗；1例失访,随访18例,术后1,3,5年生存率分别为100％、77.8％、55.6％.结论 PBL的术前诊断率低,恶性程度相对较高,局部切除联合放化疗有助于改善预后.%Objective To explore the primary breast malignant lymphoma (PBL) diagnosis methods and pathologic characteristics and prognosis. Methods From January 2001 to December 2011, The clinical pathology material and PBL follow-up results of 19 PBL patients with our hospital operative and pathological diagnosis were retrospectively analyzed; Calculating the postoperative 1, 3 and 5 years survival time. Results All cases were for postoperative pathologic and immunohistochemical diagnosis. According to Abor staging standard; Phase 1 and phase Ⅱ were 9 and 7 cases respectively, 3 cases of phase Ⅲ. Mass local resection and modified radical mastectomy were performed in 11 and 4 cases respectively, Simple mastectomy or section with reseclion for axillary lymph node dissection in 4 cases; Chemotherapy were performed in all patients, among them 7 cases of combined radi-ationtherapy; Follow-up 18 cases, postoperative 1、3 and 5 years survival rates were 100% , 77. 8% , 55. 6% respectively. Conclusion The preoperative diagnosis rate in PBL were low and the degree of malignancy relatively high, local excision combined chemoradiotherapy help to improve the prognosis.
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