中青年体检人群颈动脉粥样硬化斑块相关危险因素的Logistic回归研究

摘要

Objective To study the risk factors of carotid atherosclerotic plaque stability and incidence in young people. Methods We analyzed the natureand the integral levelof carotid atherosclerotic plaquein 307 cases of young and middle-aged peo-ple. And we analyzedthe correlation between the level of blood pressure,serum total cholesterol( TC) ,triglyceride ( TG) ,low den-sity lipoprotein cholesterol( LDL-C) ,fasting blood glucose( FBG) ,blood uric acid( UA) level and the stability and incidence of the plaque. Results ①The data in this group showed that the majority of young and middle-aged carotid atherosclerotic plaques were stable plaques with equal echo,followed by the unstable plaque with low echo.②LDL-C was correlated with the stability of plaque (P<0. 05).③TG,LDL-C and age were correlated with the incidence of plaque(P<0. 05). Conclusion LDL-C was both associ-ated with the stability and incidence of plaque,while TG and age werecorrelated with the incidence of plaque.%目的：研究影响中青年颈动脉粥样硬化斑块稳定性及发生率的危险因素。方法分析307例中青年颈动脉粥样硬化斑块的性质、积分高低,分析血压、血清总胆固醇( TC)、甘油三脂( TG)、低密度脂蛋白胆固醇( LDL-C)、空腹血糖( FBG)、血尿酸( UA)水平与斑块稳定性及发生率的相关性。结果①本组资料显示中青年颈动脉粥样硬化斑块多数为等回声的稳定斑块,其次为低回声的不稳定斑块。②LDL-C与斑块稳定性相关(P<0．05)；③TG、LDL-C、年龄与斑块发生率相关(P<0．05)。结论 LDL-C与斑块稳定性及发生率均相关,TG、年龄与斑块发生率相关。