家兔TAS1R2基因与生长发育性状的关联性分析

摘要

TAS1R2基因是味觉受体I型家族的第2个成员。本试验采集新西兰兔共417个样本，采用PCR产物直接测序法检测了家兔TAS1R2基因上的单核苷酸多态性（SNPs），分析不同基因型与日龄重的遗传效应。研究结果如下：家兔TAS1R2基因exon 6的c.1581 G>A突变基因型AA极显著影响40日龄、56日龄和84日龄家兔的体重以及35～84日龄的平均日增重（P<0.01），可考虑将TAS1R2基因作为家兔生产性状的候选基因，以期为家兔生长性状标记辅助选择提供理论依据。%TAS1R2 gene is the second member from taste receptor type I family. In this study, a total of 417 New Zealand rabbits were collected to analyze the single nucleotide polymorphism of rabbit TAS1R2 by direct sequencing method. The results as follows:genotype AA from the c.1581 G>A mutation of rabbit TAS1R2 gene in exon 6 had significant effect on rabbit′s 40-days weight, 56-days weight, 84-days weight and 35~84-days average daily gain (P<0.01). So TAS1R2 gene was considered to candidate gene of rabbit′s production traits,it might be to provide theoretical ba-sis for auxiliary selection for growth trait markers in rabbits.