99m TcO4-甲状腺显像对不同时期亚急性甲状腺炎的诊断价值

摘要

目的 探讨放射性核素99mTcO4-甲状腺显像对不同时期亚急性甲状腺炎(SAT)的诊断价值.方法 选择SAT患者155例,按甲状腺功能分为甲状腺功能亢进(甲亢)组77例、甲状腺功能正常组78例.分别行甲状腺99mTcO4-显像和细针穿刺细胞学检查(FNAB),以FNAB结果为参照,观察99mTCO4-甲状腺显像诊断不同时期SAT的灵敏度和特异度.结果 99mTcO4-甲状腺显像诊断甲亢组的灵敏度为91.7％、特异度为60.0％,与FNAB检查比较差异有统计学意义(x2=12.8,P ＜0.05)；诊断甲状腺功能正常组的灵敏度为76.1％、特异度为57.1％,与FNAB检查比较差异无统计学意义(x2=2.0,P＞0.05).结论 99mTcO4-甲状腺显像诊断甲亢期SAT敏感性和特异性均高于甲状腺功能正常期,可考虑作为首选方法.%Objective To investigate the diagnostic value of radionuclide 99mTcO4-imaging in different periods of subacute thyroiditis (SAT).Methods A total of 155 patients with SAT were divided into 2 groups,according to the thyroid function:77 cases with hyperthyroidism and 78 cases with euthyroidism.99mTcO4-thyroid imaging and fine needle aspiration biopsy (FNAB) were performed for all patients.Based on FNAB result reference,the diagnostic sensitivity and specificity of 99mTcO4-thyroid imaging in each group were observed respectively.Results The sensitivity and specificity in the hyperthyroid group were 91.7％ and 60.0％,compared to the FNAB result,with statistical difference (x2 =12.8,P ＜0.05) ; the sensitivity and specificity in the euthyroid group were 76.1％ and 57.1％,compared to the FNAB result,with no statistical difference (x2 =2.0,P ＞ 0.05).Conclusion Compared with euthyroid SAT,99mTcO4-thyroid imaging can be used as the preferred method in the diagnosis of hyperthyroid SAT,because of the higher sensitivity and specificity.