精准定性、定量评估眼前节及后节的影像学技术,不仅对多种眼病的准确诊断至关重要,同时也可为治疗方案、手术方式以及随访提供重要参考依据.作为一种分辨率高、非接触无创的成像技术,光学相干断层扫描(optical coherence tomography,OCT)已成为玻璃体视网膜相关疾病必不可少的辅助检查工具.近几年提出的扫频光学相干断层扫描成像(swept-source OCT,SS-OCT)技术,具备扫描速度提高及穿透深度加深的优点,同时运用不同成像系统可获得眼部不同层次结构精准的成像.新型的SS-OCT成像技术可用于评估眼前节结构,如角膜移植术后角膜瓣、前房参数等检查,也加深了对玻璃体视网膜相关疾病如糖尿病性黄斑病变、眼底新生血管的转归和黄斑毛细血管扩张等疾病病理形态改变的认识.同时,运用玻璃体增强成像(enhanced vitreous visualization,EVV)、分层扫描(En face SS-OCT)和SS-OCT血管造影等成像系统,可为眼底相关疾病,如玻璃体后脱离、视网膜前膜、视网膜脱离、糖尿病牵拉性视网膜脱离等手术适应证制定最佳的治疗方案并协助术后随访.此外,该技术还为多种眼部疾病如青光眼、眼肿瘤的病理形态学观察提供精准的微结构成像图.本文主要对SS-OCT的技术原理及临床应用进展等方面进行综述.%Accurate qualitative and quantitative assessment of anterior or posterior segment structures is crucial,not only for proper diagnosis of different ocular diseases but also for optimal surgical planning and postoperative follow-up.As a noninvasive and noncontact method,optical coherence tomography (OCT) has become an essential tests for the diagnosis of retinal diseases.To a more recent technology,swept-source OCT (SS-OCT) improved the depth of imaging and the scan speed,which can perform anterior segment evaluation liking corneal graft examination.Meanwhile,this newly technology add multimodal approach such as EVV,OCTA and En face OCT,for angiography and choroid mapping.Thus,SS-OCT has become a valuable imaging strategy to understand the pathologies of retinal diseases such as PVD,diabetic maculopathy,neovascularization and macular telangiectasia.With the use of multimodal approach,SS-OCT is beneficial for optimal surgical planning and postoperative follow-up for the vitreoretinal diseases,such as epiretinal membrane,retinal detachment,and diabetic taction retinal detachment.Moreover,this technology can help us better understand the ophthalmic pathologies of glaucoma and tumors.This article reviews the technical principles of SS-OCT and the advances in clinical applications.
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