睾丸非精原类生殖细胞瘤的MSCT表现与组织病理对照

摘要

Objective: To evaluate the MSCT features of testicular nonseminomatous germ cell tumors. Methods: 7 pathological proved testicular nonseminomatous germ cell tumors patients underwent MSCT and correlated them with pathological and immunohistochemical results. Results:all the 7 patients (1 endodermal sinus tumor, 2 embryonal carcinoma, 4 mixed germinoma) located in only one testiculus. AFP or/and HCG increased in 6 patients. Single side testis enlargement, solid or mixed cystic-solid mass, pathy or nodular enhancement in arterial phase and testicular artery thickening were the MSCT characters. Two cases of lymph node metastasis and 1 lung metastasis were observed. Concussion: Single side testis solid or mixed cystic-solid mass,patchy or nodular enhancement in arterial phase,early stage lymph node or hematogeneous metastasis and increase of AFP or/and HCG were the key points of nonseminomatous germ cell tumors.%目的：探讨睾丸非精原类生殖细胞瘤的MSCT特点。方法：回顾性分析7例经手术病理证实的非精原类生殖细胞瘤的MSCT表现，CT征象与病理及免疫组化结果进行对比分析。结果：内胚窦瘤1例，胚胎性癌2例，混合性生殖细胞瘤4例。7例均为单侧睾丸发病，6例伴有AFP升高，6例β-HCG升高。MSCT可见单侧睾丸增大，实性或囊实性不均质肿块。动脉期肿块内出现明显斑片、结节状强化区，7例均可见同侧睾丸动脉增粗。2例出现淋巴结转移，1例出现肺转移。结论：睾丸非精原类生殖细胞瘤为单侧睾丸起病，不均质增大的软组织肿块伴增强扫描动脉期明显斑片、结节状强化为其特征性CT表现，肿块少见局部侵犯，但早期会发生血液及淋巴道转移。结合肿瘤标记物AFP及β-HCG的升高，可做出准确的诊断。