BSAP/Pax-5在B淋巴细胞发育、增殖、分化中的作用

摘要

BSAP, a B cell lineage-specific activator protein, is a nucleus transcription factor and is en coded by the Pax-5 gene. It is a critical modulator of B cell development, proliferation and differentia tion. BSAP also influences B cell immunoglobulin secretion at later stages of B cell differentiation.%BSAp，一个B细胞特异性激活蛋白，由Pax-5转录的核蛋白。作为核转录因子，其在B细胞的发育、增殖和分化中起重要作用。同时也影响B细胞分化晚期的Ig的分泌。